2. Gene
  3. Cd4 - Cd4 molecule Gene

Cd4 - Cd4 molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: p55; W3/25

基因 ID: 24932 | 基因类型: protein coding

关于 Cd4

功能概要

Enables immunoglobulin binding activity; protein tyrosine kinase binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of calcium ion transport into cytosol; response to estradiol; and response to vitamin D. Located in external side of plasma membrane. Used to study septic arthritis and sialadenitis. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd4 基因产物(1)

mRNA Protein Name
NM_012705.1 NP_036837.1 T-cell surface glycoprotein CD4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables immunoglobulin binding IDA
IDA: 通过直接分析推断
2338715 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
1372996 RGD
enables protein tyrosine kinase binding IDA
IDA: 通过直接分析推断
8959663 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
12115612 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to ionomycin IEP
IEP: 通过表达模式推断
25678251 RGD
involved in positive regulation of T cell proliferation IMP
IMP: 通过突变表型推断
15000837 RGD
involved in positive regulation of calcium ion transport into cytosol IDA
IDA: 通过直接分析推断
8959663 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
2478646 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
8214423 RGD
involved in response to methamphetamine hydrochloride IEP
IEP: 通过表达模式推断
25678251 RGD
involved in response to vitamin D IEP
IEP: 通过表达模式推断
8759780 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
15474526 RGD
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
3159821 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

T-cell surface glycoprotein CD4

CD4 antigen

T-cell surface antigen T4/Leu-3

W3/25 antigen

重组 Cd4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72905 CD4 Protein, Rat (HEK293, His) P05540 (K28-T394) ≥95%

相关产品

Approval
生物活性分子 (5)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0689A Indinavir sulfate 99.97% 是
HY-15440A Fostemsavir Inhibitor 99.52% 否
HY-15440B Fostemsavir Tris Inhibitor 99.94% 否
HY-B0689 Indinavir / 否
HY-B0689B Indinavir sulfate ethanolate / 否
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P99222 Teplizumab ≥99.0% 否
HY-P99028 Ibalizumab Inhibitor 99.52% 否
Clinical Phase
生物活性分子 (6)
目录号 产品名 作用方式
纯度 Phase
HY-105037A Forigerimod TFA Inhibitor 98.89% Phase 3
HY-148808 Zelasudil Inhibitor 99.86% Phase 2
HY-P0272 Peptide T Inhibitor 98.86% Phase 2
HY-14135 BMS 488043 Inhibitor / Phase 2
HY-P0272A Peptide T TFA Inhibitor / Phase 2
HY-15440 Temsavir Inhibitor 98.06% Phase 1
抗体抑制剂 (4)
目录号 产品名 作用方式
纯度 Phase
HY-P9998 Semzuvolimab Inhibitor 95.00% Phase 3
HY-P99908 Efineptakin alfa Activator 99.70% Phase 2
HY-P99607 Clenoliximab Inhibitor / Phase 2
HY-P99433 Alvircept sudotox Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (71)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150741 ODN 2216 / 否
HY-110382 Cyclic-di-GMP disodium Activator 99.23% 否
HY-150741C ODN 2216 sodium Activator 97.88% 否
HY-107780B Cyclic-di-GMP diammonium Activator 99.07% 否
HY-15898 Y-320 99.74% 否
HY-P2560 LCMV GP (61-80) 99.80% 否
HY-134809 Cyclotriazadisulfonamide Inhibitor 98.54% 否
HY-124750 NecroX-7 Inhibitor 99.69% 否
HY-P1066 Apelin-17(human, bovine) 98.29% 否
HY-155978A RDN2150 TFA 99.62% 否
HY-119347 Cirsilineol Inhibitor ≥98.0% 否
HY-P1064 Apelin-36(human) 98.05% 否
HY-139780 JNJ-61803534 Inhibitor 99.88% 否
HY-Y0788 Indoline 99.89% 否
HY-14134 BMS-378806 Inhibitor 98.94% 否
HY-107780 Cyclic-di-GMP Activator 98.18% 否
HY-157793 SMU-L11 99.64% 否
HY-P1997 Ferrichrome Iron-free ≥98.0% 否
HY-12465 Z-Ile-Leu-aldehyde 97.28% 否
HY-P1065 Apelin-36(rat, mouse) 99.12% 否
HY-W181026 KLF10-IN-1 99.84% 否
HY-164426 HEI3090 Activator 99.04% 否
HY-100039 YYA-021 Inhibitor 98.96% 否
HY-105037 Forigerimod Inhibitor / 否
HY-138115 7ß,27-Dihydroxycholesterol Activator ≥99.0% 否
HY-148432 FGF22-IN-1 Inhibitor 98.07% 否
HY-155978 RDN2150 / 否
HY-P1064A Apelin-36(human) TFA 98.11% 否
HY-P1409A ADWX 1 TFA Inhibitor / 否
HY-16106S Talazoparib-13C,d4 99.30% 否
HY-76648 NBD-556 Inhibitor 99.57% 否
HY-W102449S 4-Acetyl-N-methylaniline-13C,d3 97.05% 否
HY-135432 Etrasimod arginine Modulator / 否
HY-106055 Murabutide Inhibitor / 否
HY-107780A Cyclic-di-GMP sodium Activator / 否
HY-111366 CD12681 Agonist / 否
HY-119202 (S)-BMS-378806 / 否
HY-121820 DMJ-I-228 Inhibitor / 否
HY-123312 CK-548 Inhibitor / 否
HY-123902 Ophiobolin C Inhibitor / 否
HY-126037 (±)-ML 209 Antagonist 99.87% 否
HY-128790S 4-Methoxyestrone-13C,d3 / 否
HY-137618B Rp-dGTPαS / 否
HY-137640A Sp-8-Br-cAMPS sodium Agonist / 否
HY-144746 PD-1/PD-L1-IN-26 Inhibitor / 否
HY-145491 Resolvin D5 / 否
HY-15091 Anisperimus / 否
HY-159123 KHK-6 Inhibitor / 否
HY-161255 3,4-DAA Inhibitor / 否
HY-169335 HIV-1 inhibitor-77 Inhibitor / 否
HY-B0094S3 Artemisinin-13C,d4 / 否
HY-P10308 [(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) / 否
HY-P1065A Apelin-36(rat, mouse) TFA / 否
HY-P1066A Apelin-17(human, bovine) TFA / 否
HY-P2561 Influenza Matrix Protein (61-72) / 否
HY-P3554 Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl Inhibitor / 否
HY-P4902 Retrocyclin-1 Inhibitor / 否
HY-P5930 HOXB7 8–25 / 否
HY-RS02245 CD4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W005355S8 Sodium 2-oxobutanoate-13C,d4 / 否
HY-W006057AS14 Sodium 3-methyl-2-oxobutanoate-13C,d4 / 否
HY-W780197 Methanol-13C,d4 / 否
HY-Y0781S5 Pyruvic acid-13C,d4 / 否
HY-117160S2 4-trans-Hydroxy glibenclamide-13C,d4 / 否
HY-123756 NBD-10007 Inhibitor / 否
HY-12926 ST7612AA1 / 否
HY-134809A Cyclotriazadisulfonamide hydrochloride / 否
HY-13644 Gusperimus / 否
HY-154771S Clopidogrelat-13C,d4 / 否
HY-B0202S4 Irbesartan-13C,d4 / 否
HY-110216 5J-4 Inhibitor 95% 否
抗体抑制剂 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99999 Anti-Mouse CD4 Antibody (YTS 191) Inhibitor ≥95.0% 否
HY-P99680 Keliximab Inhibitor 98.23% 否
HY-P990969 Amtabafusp alfa Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd4 NCBI NCBI:920
Canis familiaris Cd4 NCBI NCBI:403931
Macaca fascicularis Cd4 NCBI NCBI:101864991
Mus musculus Cd4 NCBI NCBI:12504
Leporidae Cd4 NCBI
Macaca mulatta Cd4 NCBI NCBI:713807
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