LHX6 - LIM homeobox 6 Gene

中文名称：LIM 同源框 6

种属: Homo sapiens

同用名: hLHX6; LHX6.1

关于 LHX6

功能概要

该基因编码一个包含 LIM 结构域的大型蛋白质家族成员，LIM 结构域是一个独特的富含半胱氨酸的锌结合结构域。编码的蛋白质具有串联 LIM 结构域以及 DNA 结合同源结构域。该蛋白质作为参与胚胎发生和头部发育的转录因子发挥作用，并在神经嵴衍生的间充质细胞中高度表达。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2017 年 1 月]

This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein has tandem LIM domains as well as a DNA-binding homeodomain. The protein functions as a transcription factor involved in embryogenesis and head development and is highly expressed in neural crest derived mesenchyme cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]