1. Gene
  2. SSC5D - scavenger receptor cysteine rich family member with 5 domains Gene

SSC5D - scavenger receptor cysteine rich family member with 5 domains Gene

中文名称:具有 5 个结构域的富半胱氨酸的清道夫受体家族成员

种属: Homo sapiens

同用名: S5D-SRCRB

基因 ID: 284297 | 基因类型: protein coding

关于 SSC5D

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:55,488,436-55,519,099 (from NCBI)

This gene has 5 transcripts (splice variants), 397 orthologues and 15 paralogues. Broad expression in gall bladder (RPKM 7.3), endometrium (RPKM 6.2) and 21 other tissues.

功能概要

预测启用纤连蛋白结合活性;层粘连蛋白结合活性;和清道夫受体活性。预计参与防御反应;细菌脂蛋白检测;白细胞介素 8 产生的负调节。预计在白细胞介素 8 生产的调节上游或调节范围内起作用。预计位于含胶原蛋白的细胞外基质中。预计在细胞外基质和细胞外空间中具有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable fibronectin binding activity; laminin binding activity; and scavenger receptor activity. Predicted to be involved in defense response; detection of Bacterial lipoprotein; and negative regulation of interleukin-8 production. Predicted to act upstream of or within regulation of interleukin-8 production. Predicted to be located in collagen-containing extracellular matrix. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SSC5D 基因产物(2)

mRNA Protein Name
NM_001144950.2 NP_001138422.1 soluble scavenger receptor cysteine-rich domain-containing protein SSC5D isoform 1 precursor
NM_001195267.2 NP_001182196.1 soluble scavenger receptor cysteine-rich domain-containing protein SSC5D isoform 2 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SSC5D 蛋白结构

SRCR

SRCR: Scavenger receptor cysteine-rich domain (24 - 119)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (201 - 298)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (308 - 403)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (470 - 568)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (776 - 872)

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  • 1573 a.a.
蛋白主名 其他名称

soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

SSC5D 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SSC5D A1L4H1 NECAB2 Homo sapiens Q7Z6G3-2 32296183
种属内
SSC5D A1L4H1 NECAB2 Homo sapiens Q7Z6G3-2 25416956
种属内
SSC5D A1L4H1 NECAB2 Homo sapiens Q7Z6G3-2 32296183
种属内
SSC5D A1L4H1 NECAB2 Homo sapiens Q7Z6G3-2 32296183
种属内
SSC5D A1L4H1 SEC23IP Homo sapiens Q9Y6Y8 25416956
种属内
SSC5D A1L4H1 SEC23IP Homo sapiens Q9Y6Y8 25416956
种属内
SSC5D A1L4H1 SEC23IP Homo sapiens Q9Y6Y8 32296183
种属内
SSC5D A1L4H1 SEC23IP Homo sapiens Q9Y6Y8 32296183
种属内
SSC5D A1L4H1 SEC23IP Homo sapiens Q9Y6Y8 32296183
种属内
SSC5D A1L4H1 HAUS1 Homo sapiens Q96CS2 32296183
种属内
SSC5D A1L4H1 HAUS1 Homo sapiens Q96CS2 32296183
种属内
SSC5D A1L4H1 HAUS1 Homo sapiens Q96CS2 32296183
种属内
SSC5D A1L4H1 KRT27 Homo sapiens Q7Z3Y8 32296183
种属内
SSC5D A1L4H1 KRT27 Homo sapiens Q7Z3Y8 32296183
种属内
SSC5D A1L4H1 KRT27 Homo sapiens Q7Z3Y8 32296183
种属内
SSC5D A1L4H1 NUP62 Homo sapiens P37198 25416956
种属内
SSC5D A1L4H1 NUP62 Homo sapiens P37198 32296183
种属内
SSC5D A1L4H1 NUP62 Homo sapiens P37198 32296183
种属内
SSC5D A1L4H1 NUP62 Homo sapiens P37198 32296183
种属内
SSC5D A1L4H1 TRAF1 Homo sapiens Q13077 25416956
种属内
SSC5D A1L4H1 MED29 Homo sapiens Q9NX70 32296183
种属内
SSC5D A1L4H1 MED29 Homo sapiens Q9NX70 32296183
种属内
SSC5D A1L4H1 MED21 Homo sapiens Q13503 32296183
种属内
SSC5D A1L4H1 MED21 Homo sapiens Q13503 32296183
种属内
SSC5D A1L4H1 MED21 Homo sapiens Q13503 25416956
种属内
SSC5D A1L4H1 MED21 Homo sapiens Q13503 32296183
种属内
SSC5D A1L4H1 MED11 Homo sapiens Q9P086 32296183
种属内
SSC5D A1L4H1 MED11 Homo sapiens Q9P086 32296183
种属内
SSC5D A1L4H1 MED11 Homo sapiens Q9P086 32296183
种属内
SSC5D A1L4H1 DTNBP1 Homo sapiens Q96EV8 25416956
种属内
SSC5D A1L4H1 BLOC1S2 Homo sapiens Q6QNY1 32296183
种属内
SSC5D A1L4H1 BLOC1S2 Homo sapiens Q6QNY1 32296183
种属内
SSC5D A1L4H1 BLOC1S2 Homo sapiens Q6QNY1 32296183
种属内
SSC5D A1L4H1 EXOC7 Homo sapiens Q9UPT5-1 32296183
种属内
SSC5D A1L4H1 EXOC7 Homo sapiens Q9UPT5-1 32296183
种属内
SSC5D A1L4H1 EXOC7 Homo sapiens Q9UPT5-1 32296183
种属内
SSC5D A1L4H1 TCEA2 Homo sapiens Q15560 32296183
种属内
SSC5D A1L4H1 PIN1 Homo sapiens Q13526 32296183
种属内
SSC5D A1L4H1 EXOC7 Homo sapiens Q9UPT5 25416956
种属内
SSC5D A1L4H1 SDCBP Homo sapiens O00560 32296183
种属内
SSC5D A1L4H1 SKA1 Homo sapiens Q96BD8 32296183
种属内
SSC5D A1L4H1 SKA1 Homo sapiens Q96BD8 32296183
种属内
SSC5D A1L4H1 SKA1 Homo sapiens Q96BD8 32296183
种属内
SSC5D A1L4H1 CEP170P1 Homo sapiens Q96L14 25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Nasal Type Extranodal Nk/T-Cell Lymphoma

Extranodal Nasal Nk/T Cell Lymphoma

Angiocentric T-Cell Lymphoma

Lethal Midline Granuloma

Nk/T-Cell Lymphoma

Nktcl

Nasal T/Natural Killer-Cell Lymphoma

Granuloma, Lethal Midline

Nasal And Nasal-Type Nk/T-Cell Lymphoma

Adenoiditis

Chronic Adenoiditis

Vitreous Detachment

Posterior Vitreous Detachment

Vitreous Syneresis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SSC5D VGNC VGNC:53993
Felis catus SSC5D VGNC VGNC:82391
Mus musculus SSC5D MGD MGI:3606211
Rattus norvegicus SSC5D RGD RGD:1565772
Bos taurus SSC5D VGNC VGNC:35310