2. Gene
  3. MED29 - mediator complex subunit 29 Gene

MED29 - mediator complex subunit 29 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：介体复合体亚基 29

种属: Homo sapiens

同用名: IXL; MED2

基因 ID: 55588 | 基因类型: protein coding

关于 MED29

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,391,378-39,400,641 (from NCBI)

This gene has 6 transcripts (splice variants) and 88 orthologues. Ubiquitous expression in brain (RPKM 2.7), thyroid (RPKM 2.6) and 25 other tissues.

功能概要

MED29 是 Mediator 复合体的一个亚基，它是 RNA 转录的多蛋白共激活因子，与 DNA 结合的转录激活因子、RNA 聚合酶 II (参见 MIM 180660) 和一般起始因子相互作用 (Sato 等人，2003 [PubMed 14576168]) 。[OMIM 提供，2009 年 8 月]

MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2003 [PubMed 14576168]).[supplied by OMIM, Aug 2009]

MED29 基因产物(2)

mRNA Protein Name
NM_001317770.3 NP_001304699.2 mediator of RNA polymerase II transcription subunit 29 isoform 2
NM_017592.4 NP_060062.2 mediator of RNA polymerase II transcription subunit 29 isoform 1

MED29 蛋白结构

Med29

Med29: Mediator complex subunit 29 (51 - 188)

  • 0
  • 100
  • 200 a.a.
蛋白主名 其他名称

mediator of RNA polymerase II transcription subunit 29

intersex-like protein

MED29 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MED29 Q9NX70 SSC5D Homo sapiens A1L4H1
Y2H Prey Pooling
32296183
Intra MED29 Q9NX70 ABI2 Homo sapiens Q9NYB9-2
Validated Y2H
32296183
Cross MED29 Q9NX70 Med30 Mus musculus Q9CQI9
Anti Tag CoIP
24882805
Intra MED29 Q9NX70 MED19 Homo sapiens A0JLT2
Anti Tag CoIP
33961781
Intra MED29 Q9NX70 MED19 Homo sapiens A0JLT2
Anti Tag CoIP
15175163
Intra MED29 Q9NX70 MED19 Homo sapiens A0JLT2
Anti Tag CoIP
14638676
Intra MED29 Q9NX70 MED6 Homo sapiens O75586
Anti Tag CoIP
14576168
Intra MED29 Q9NX70 MED6 Homo sapiens O75586
Anti Tag CoIP
35271311
Intra MED29 Q9NX70 MED6 Homo sapiens O75586
Anti Tag CoIP
15175163
Intra MED29 Q9NX70 MED6 Homo sapiens O75586
Anti Tag CoIP
33961781
Intra MED29 Q9NX70 MED6 Homo sapiens O75586
Anti Tag CoIP
24882805
Intra MED29 Q9NX70 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
24882805
Intra MED29 Q9NX70 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
33961781
Intra MED29 Q9NX70 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
14576168
Intra MED29 Q9NX70 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
35271311
Intra MED29 Q9NX70 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
14638676
Intra MED29 Q9NX70 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
15175163
Intra MED29 Q9NX70 MED20 Homo sapiens Q9H944
Anti Tag CoIP
35271311
Intra MED29 Q9NX70 MED20 Homo sapiens Q9H944
Anti Tag CoIP
14576168
Intra MED29 Q9NX70 MED20 Homo sapiens Q9H944
Anti Tag CoIP
33961781
Intra MED29 Q9NX70 MED20 Homo sapiens Q9H944
Chromatography
14576168
Intra MED29 Q9NX70 MED20 Homo sapiens Q9H944
Anti Tag CoIP
15175163
Intra MED29 Q9NX70 MED22 Homo sapiens Q15528
Anti Tag CoIP
33961781
Intra MED29 Q9NX70 MED22 Homo sapiens Q15528
Anti Tag CoIP
15175163
Intra MED29 Q9NX70 MED22 Homo sapiens Q15528
Anti Tag CoIP
14638676
Intra MED29 Q9NX70 MED22 Homo sapiens Q15528
Anti Tag CoIP
35271311
Intra MED29 Q9NX70 MED28 Homo sapiens Q9H204
Anti Tag CoIP
33961781
Intra MED29 Q9NX70 MED28 Homo sapiens Q9H204
Anti Tag CoIP
15175163
Intra MED29 Q9NX70 MED28 Homo sapiens Q9H204
Anti Tag CoIP
35271311
Cross MED29 Q9NX70 Med11 Mus musculus Q9D8C6
Anti Tag CoIP
24882805
Intra MED29 Q9NX70 ABI3 Homo sapiens Q9P2A4
Validated Y2H
32296183
Cross MED29 Q9NX70 Med8 Mus musculus Q9D7W5
Anti Tag CoIP
24882805
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Fleck Retina, Familial Benign

FRFB

Familial Benign Flecked Retina

Familial Benign Fleck Retina
Fetishism

Fetishism, Psychiatric
Bubonic Plague

Black Death

Plague, Bubonic

Plague, Septicemic

Pestis Bubonica
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08300 MED29 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus MED29 MGD MGI:1914474
Canis familiaris MED29 VGNC VGNC:43136
Rattus norvegicus MED29 RGD RGD:1311009
Macaca mulatta MED29 VGNC VGNC:74557
Bos taurus MED29 VGNC VGNC:31365
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