CXCL17 - C-X-C motif chemokine ligand 17 Gene

中文名称：CXC 基序趋化因子配体 17

种属: Homo sapiens

同用名: DMC; VCC1; Dcip1; VCC-1; UNQ473

关于 CXCL17

功能概要

该基因编码的蛋白质是一种粘膜趋化因子，可将未成熟的树突状细胞和血液单核细胞吸引到肺部。编码的蛋白质还通过血管生成活性促进肿瘤发生。最后，这种蛋白质对大肠杆菌、金黄色葡萄球菌、沙门氏菌、铜绿假单胞菌和白色念珠菌表现出很强的抗菌活性。已发现该基因的两种转录变体，一种是蛋白质编码，另一种是非蛋白质编码。[RefSeq 提供，2015 年 12 月]

The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the Other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]