2. Gene
  3. GTF2A1 - general transcription factor IIA subunit 1 Gene

GTF2A1 - general transcription factor IIA subunit 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：一般转录因子 IIA 亚基 1

种属: Homo sapiens

同用名: TF2A1; TFIIA; TFIIAL; TFIIA-42

基因 ID: 2957 | 基因类型: protein coding

关于 GTF2A1

Cytogenetic location: 14q31.1 Genomic coordinates (GRCh38): 14:81,175,452-81,221,390 (from NCBI)

This gene has 4 transcripts (splice variants), 213 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 15.3), testis (RPKM 12.9) and 25 other tissues.

功能概要

包含 TATA 的 II 类基因的准确转录起始涉及 RNA 聚合酶 II (POLR2A；MIM 180660) 和几个一般起始因子的有序组装 (由 DeJong 和 Roeder 总结，1993 [PubMed 8224848]) 。其中一个因素是 TFIIA，当从 HeLa 提取物中纯化时，它由 35、19 和 12 kD 亚基组成。[OMIM 提供，2010 年 7 月]

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]

GTF2A1 基因产物(3)

mRNA Protein Name
NM_001278940.2 NP_001265869.1 transcription initiation factor IIA subunit 1 isoform 3
NM_015859.4 NP_056943.1 transcription initiation factor IIA subunit 1 isoform 1
NM_201595.3 NP_963889.1 transcription initiation factor IIA subunit 1 isoform 2

GTF2A1 蛋白结构

TFIIA

TFIIA: Transcription factor IIA, alpha/beta subunit (12 - 376)

  • 0
  • 100
  • 200
  • 300
  • 376 a.a.
蛋白主名 其他名称

transcription initiation factor IIA subunit 1

TFIIA alpha/beta subunits

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05892 GTF2A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05896 GTF2F1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05898 GTF2H1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05904 GTF2IRD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus GTF2A1 MGD MGI:1933277
Bos taurus GTF2A1 VGNC VGNC:29691
Canis familiaris GTF2A1 VGNC VGNC:41541
Macaca mulatta GTF2A1 VGNC VGNC:73305
Rattus norvegicus GTF2A1 RGD RGD:69246
Felis catus GTF2A1 VGNC VGNC:104398
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