2. Gene
  3. NUBP1 - NUBP iron-sulfur cluster assembly factor 1, cytosolic Gene

NUBP1 - NUBP iron-sulfur cluster assembly factor 1, cytosolic Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：NUBP 铁硫簇组装因子 1，胞质

种属: Homo sapiens

同用名: NBP; NBP1; CIAO5; NBP35

基因 ID: 4682 | 基因类型: protein coding

关于 NUBP1

Cytogenetic location: 16p13.13 Genomic coordinates (GRCh38): 16:10,743,842-10,769,351 (from NCBI)

This gene has 8 transcripts (splice variants), 207 orthologues and 2 paralogues. Ubiquitous expression in adrenal (RPKM 9.0), heart (RPKM 8.6) and 25 other tissues.

功能概要

NUBP1 是 ATP 结合蛋白 NUBP/MRP 亚家族的成员 (Nakashima 等人，1999 [PubMed 10486206]) 。[OMIM 提供，2008 年 3 月]

NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]

NUBP1 基因产物(6)

mRNA Protein Name
NM_001278506.2 NP_001265435.1 cytosolic Fe-S cluster assembly factor NUBP1 isoform 2
NM_001323594.2 NP_001310523.1 cytosolic Fe-S cluster assembly factor NUBP1 isoform 3
NM_001323595.2 NP_001310524.1 cytosolic Fe-S cluster assembly factor NUBP1 isoform 4
NM_001323596.2 NP_001310525.1 cytosolic Fe-S cluster assembly factor NUBP1 isoform 5
NM_001323597.1 NP_001310526.1 cytosolic Fe-S cluster assembly factor NUBP1 isoform 6
NM_002484.4 NP_002475.2 cytosolic Fe-S cluster assembly factor NUBP1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables iron-sulfur cluster binding IDA
IDA: 通过直接分析推断
18573874 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
18573874 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
18573874 GOA
involved in iron-sulfur cluster assembly IMP
IMP: 通过突变表型推断
18573874 GOA
involved in regulation of cell growth IMP
IMP: 通过突变表型推断
18573874 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
18573874 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NUBP1 蛋白结构

ArsA_ATPase

ArsA_ATPase: Anion-transporting ATPase (55 - 85)

ParA

ParA: NUBPL iron-transfer P-loop NTPase (165 - 246)

  • 0
  • 100
  • 200
  • 300
  • 320 a.a.
蛋白主名 其他名称

cytosolic Fe-S cluster assembly factor NUBP1

NBP 1

NUBP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
NUBP1 P53384 NUBP2 Homo sapiens Q9Y5Y2
Anti Tag CoIP
18573874
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Pica Disease

Pica
Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 6

Mitochondrial Dna Deletion Syndrome With Progressive Myopathy

PEOA6

Autosomal Dominant Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions 6

Dna2-Related Mitochondrial Dna Deletion Syndrome

Mitochondrial Dna Deletion Syndrome With Limb-Girdle Weakness

Mtdna Deletion Syndrome With Limb-Girdle Weakness

Mtdna Deletion Syndrome With Progressive Myopathy

Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant, 6

Progressive External Ophthalmoplegia, Autosomal Dominant 6

Autosomal Dominant Progressive External Ophthalmoplegia 6

Progressive External Ophthalmoplegia Autosomal Dominant 6

Ophthalmoplegia, External, Progressive, With Mitochondrial Dna Deletions, Autosomal Dominant, Type 6
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09651 NUBP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris NUBP1 VGNC VGNC:44017
Felis catus NUBP1 VGNC VGNC:68584
Macaca mulatta NUBP1 VGNC VGNC:75546
Rattus norvegicus NUBP1 RGD RGD:1310514
Bos taurus NUBP1 VGNC VGNC:32315
Mus musculus NUBP1 MGD MGI:1347073
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