ATP1B3 - ATPase Na+/K+ transporting subunit beta 3 Gene

中文名称：ATPase Na+/K+ 转运亚基 β 3

种属: Homo sapiens

同用名: CD298; ATPB-3

关于 ATP1B3

功能概要

该基因编码的蛋白质属于 Na+/K+ 和 H+/K+ ATPases β 链蛋白家族，以及 Na+/K+ -ATPases 亚家族。 Na+/K+ -ATPase 是一种完整的膜蛋白，负责建立和维持 Na 和 K 离子跨质膜的电化学梯度。这些梯度对于渗透调节、各种有机和无机分子的钠偶联转运以及神经和肌肉的电兴奋性至关重要。这种酶由两个亚基组成，一个大的催化亚基 (α) 和一个较小的糖蛋白亚基 (β) 。 β 亚基通过组装 α/β 异二聚体来调节输送到质膜的钠泵的数量。 Na+/K+ -ATPase 的糖蛋白亚基由多个基因编码。该基因编码一个 β 3 亚基。该基因编码一个 β 3 亚基。该基因存在假基因，位于 2 号染色体上。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This Enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]