STX18 - syntaxin 18 Gene

中文名称：突触 18

种属: Homo sapiens

同用名: Ufe1

关于 STX18

功能概要

该基因编码可溶性 N-乙基马来酰亚胺敏感因子附着蛋白受体 (SNARE) 的突触融合蛋白家族成员，它是包括其他 SNARE 和几种外周膜蛋白的膜束缚复合物的一部分，并参与内质细胞之间的囊泡运输网状结构 (ER) 和高尔基复合体。编码的蛋白质对于平滑、粗糙和退出站点 ER 子域的组织很重要。已鉴定出该基因的假基因。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 10 月]

This gene encodes a member of the syntaxin family of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) which is part of a membrane tethering complex that includes Other SNAREs and several peripheral membrane proteins, and is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi complex. The encoded protein is important for the organization of the smooth, rough, and exit site ER subdomains. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]