1. Gene
  2. PNLIPRP1 - pancreatic lipase related protein 1 Gene

PNLIPRP1 - pancreatic lipase related protein 1 Gene

中文名称:胰脂肪酶相关蛋白 1

种属: Homo sapiens

同用名: PLRP1

基因 ID: 5407 | 基因类型: protein coding

关于 PNLIPRP1

Cytogenetic location: 10q25.3 Genomic coordinates (GRCh38): 10:116,590,959-116,609,175 (from NCBI)

This gene has 21 transcripts (splice variants), 136 orthologues and 9 paralogues. Restricted expression toward pancreas (RPKM 974.1).

功能概要

预测可启用钙离子结合活性。预计参与脂质分解代谢过程。预测位于细胞外区域。前列腺癌的生物标志物。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable calcium ion binding activity. Predicted to be involved in lipid catabolic process. Predicted to be located in extracellular region. Biomarker of prostate Cancer. [provided by Alliance of Genome Resources, Apr 2022]

PNLIPRP1 基因产物(2)

mRNA Protein Name
NM_001303135.1 NP_001290064.1 inactive pancreatic lipase-related protein 1 precursor
NM_006229.4 NP_006220.1 inactive pancreatic lipase-related protein 1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables lipase activity IDA
IDA: 通过直接分析推断
19824014 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
NOT located in extracellular space IDA
IDA: 通过直接分析推断
19824014 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PNLIPRP1 蛋白结构

Lipase

Lipase: Lipase (18 - 353)

PLAT

PLAT: PLAT/LH2 domain (358 - 460)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 467 a.a.
蛋白主名 其他名称

inactive pancreatic lipase-related protein 1

重组 PNLIPRP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70991 PLRP1 Protein, Human (HEK293, His) AAH25784.1 (K18-C467) ≥95%

关联疾病

疾病名称 别名
Macular Degeneration, Age-Related, 10

ARMD10

Age Related Macular Degeneration 10

Macular Degeneration, Age-Related, Type 10

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris PNLIPRP1 VGNC VGNC:44746
Macaca mulatta PNLIPRP1 VGNC VGNC:76198
Rattus norvegicus PNLIPRP1 RGD RGD:620792
Mus musculus PNLIPRP1 MGD MGI:97723
Canis lupus familiaris PNLIPRP1 NCBI
Others PNLIPRP1 NCBI