2. Gene
  3. MFSD6 - major facilitator superfamily domain containing 6 Gene

MFSD6 - major facilitator superfamily domain containing 6 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含主要促进超家族结构域 6

种属: Homo sapiens

同用名: MMR2; hMMR2

基因 ID: 54842 | 基因类型: protein coding

关于 MFSD6

Cytogenetic location: 2q32.2 Genomic coordinates (GRCh38): 2:190,407,576-190,502,314 (from NCBI)

This gene has 10 transcripts (splice variants), 253 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 26.0), thyroid (RPKM 22.9) and 23 other tissues.

功能概要

预测启用 MHC I 类蛋白结合活性和 MHC I 类受体活性。预计通过 MHC I 类参与抗原加工和外源肽抗原的呈递。位于膜中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable MHC class I protein binding activity and MHC class I receptor activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class I. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

MFSD6 基因产物(9)

mRNA Protein Name
NM_001375986.1 NP_001362915.1 major facilitator superfamily domain-containing protein 6 isoform a
NM_001375987.1 NP_001362916.1 major facilitator superfamily domain-containing protein 6 isoform a
NM_001375988.1 NP_001362917.1 major facilitator superfamily domain-containing protein 6 isoform a
NM_001375989.1 NP_001362918.1 major facilitator superfamily domain-containing protein 6 isoform b
NM_001375990.1 NP_001362919.1 major facilitator superfamily domain-containing protein 6 isoform b
NM_001375992.1 NP_001362921.1 major facilitator superfamily domain-containing protein 6 isoform b
NM_001375993.1 NP_001362922.1 major facilitator superfamily domain-containing protein 6 isoform c
NM_001375994.1 NP_001362923.1 major facilitator superfamily domain-containing protein 6 isoform d
NM_017694.4 NP_060164.3 major facilitator superfamily domain-containing protein 6 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MFSD6 蛋白结构

MFS_1_like

MFS_1_like: MFS_1 like family (70 - 142)

MFS_1

MFS_1: Major Facilitator Superfamily (450 - 643)

  • 0
  • 200
  • 400
  • 600
  • 791 a.a.
蛋白主名 其他名称

major facilitator superfamily domain-containing protein 6

macrophage MHC class I receptor 2 homolog

MFSD6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MFSD6 Q6ZSS7 SDC3 Homo sapiens A0A0S2Z4U3
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SDC3 Homo sapiens A0A0S2Z4U3
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 TMEM242 Homo sapiens Q9NWH2
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 TMEM242 Homo sapiens Q9NWH2
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 TMEM242 Homo sapiens Q9NWH2
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SGPL1 Homo sapiens O95470
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SGPL1 Homo sapiens O95470
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 AQP7 Homo sapiens Q6P5T0
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 AQP7 Homo sapiens Q6P5T0
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 TMEM179B Homo sapiens Q7Z7N9
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 TMEM179B Homo sapiens Q7Z7N9
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 TMEM179B Homo sapiens Q7Z7N9
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 MFSD4B Homo sapiens Q5TF39
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 MFSD4B Homo sapiens Q5TF39
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 TMEM258 Homo sapiens P61165
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 TMEM258 Homo sapiens P61165
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SLC39A2 Homo sapiens Q9NP94
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SLC39A2 Homo sapiens Q9NP94
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SLC39A2 Homo sapiens Q9NP94
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 PDCD1LG2 Homo sapiens Q9BQ51
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SSMEM1 Homo sapiens Q8WWF3
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SLC18A1 Homo sapiens P54219-3
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SLC18A1 Homo sapiens P54219-3
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SHISAL1 Homo sapiens Q3SXP7
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SHISAL1 Homo sapiens Q3SXP7
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 LY6E Homo sapiens Q16553
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 LY6E Homo sapiens Q16553
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 C19orf18 Homo sapiens Q8NEA5
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 C19orf18 Homo sapiens Q8NEA5
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 C19orf18 Homo sapiens Q8NEA5
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 APH1A Homo sapiens Q96BI3
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 APH1A Homo sapiens Q96BI3
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 APH1A Homo sapiens Q96BI3
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 STX12 Homo sapiens Q86Y82
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 GJB2 Homo sapiens P29033
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 GJB2 Homo sapiens P29033
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 ALG8 Homo sapiens Q9BVK2
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SYNDIG1 Homo sapiens Q9H7V2
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 SYNDIG1 Homo sapiens Q9H7V2
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 SYNDIG1 Homo sapiens Q9H7V2
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra MFSD6 Q6ZSS7 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra MFSD6 Q6ZSS7 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra MFSD6 Q6ZSS7 SELENOK Homo sapiens Q9Y6D0
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Herpangina

Vesicular Pharyngitis
West Nile Encephalitis

West-Nile Encephalitis

West Nile Fever

West Nile Fever Encephalitis

West Nile Fever With Encephalitis

West-Nile Fever

Encephalitis, West Nile Fever
Salivary Gland Disease

Salivary Gland Disorders

Salivary Gland Diseases

Non-Neoplastic Salivary Gland Disease

Non-Neoplastic Salivary Gland Disorder

Disorder Of Salivary Gland

Lesion Of Salivary Gland Nos
Tetanus Neonatorum

Neonatal Tetanus

NNT

Trismus Neonatorum

Newborn Trismus
Cutaneous Diphtheria

Diphtheria Wound Infection
Parotid Disease

Parotid Diseases
Orchitis

Inflammation Of Testis

Orchititis

Mumps Orchitis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08393 MFSD6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MFSD6 VGNC VGNC:74571
Mus musculus MFSD6 MGD MGI:1922925
Felis catus MFSD6 VGNC VGNC:63484
Bos taurus MFSD6 VGNC VGNC:31441
Rattus norvegicus MFSD6 RGD RGD:1562317
Canis familiaris MFSD6 VGNC VGNC:43205
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