TRMT10C - tRNA methyltransferase 10C, mitochondrial RNase P subunit Gene

中文名称：tRNA 甲基转移酶 10C，线粒体 RNase P 亚基

种属: Homo sapiens

同用名: HNYA; MRPP1; COXPD30; RG9MTD1

基因 ID: 54931 | 基因类型: protein coding

关于 TRMT10C

Cytogenetic location: 3q12.3 Genomic coordinates (GRCh38): 3:101,561,868-101,566,446 (from NCBI)

This gene has 2 transcripts (splice variants), 184 orthologues, 2 paralogues and is associated with 3 phenotypes. Ubiquitous expression in adrenal (RPKM 10.2), lymph node (RPKM 9.9) and 25 other tissues.

功能概要

该基因编码线粒体核糖核酸酶 P 亚基的前体，参与线粒体 tRNA 的 5' 加工。编码的蛋白质可能赋予线粒体核糖核酸酶 P RNA 结合能力，并且可能对转录物加工、RNA 修饰、翻译和线粒体呼吸至关重要。[RefSeq 提供，2012 年 11 月]

This gene encodes the precursor of a subunit of the mitochondrial ribonuclease P, which is involved in 5' processing of mitochondrial tRNAs. The encoded protein may confer RNA-binding capacity to mitochondrial ribonuclease P and may be essential for transcript processing, RNA modification, translation and mitochondrial respiration. [provided by RefSeq, Nov 2012]

TRMT10C 基因产物(1)

mRNA	Protein	Name
NM_017819.4	NP_060289.2	tRNA methyltransferase 10 homolog C precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables identical protein binding	IPI IPI: 通过物理相互作用推断	29880640	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	18984158	GOA
enables tRNA (adenine(9)-N1)-methyltransferase activity	IDA IDA: 通过直接分析推断	23042678	GOA
enables tRNA (guanosine(9)-N1)-methyltransferase activity	IDA IDA: 通过直接分析推断	23042678	GOA
enables tRNA binding	IDA IDA: 通过直接分析推断	29040705	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in mRNA processing	IDA IDA: 通过直接分析推断	29072297	GOA
involved in mitochondrial RNA 5'-end processing	IMP IMP: 通过突变表型推断	21593607	GOA
involved in mitochondrial tRNA 3'-end processing	IDA IDA: 通过直接分析推断	29040705	GOA
involved in mitochondrial tRNA 5'-end processing	IDA IDA: 通过直接分析推断	29040705	GOA
involved in mitochondrial tRNA methylation	IDA IDA: 通过直接分析推断	23042678	GOA
involved in mitochondrial tRNA processing	IMP IMP: 通过突变表型推断	27132592	GOA
involved in positive regulation of mitochondrial translation	IMP IMP: 通过突变表型推断	27132592	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in mitochondrial nucleoid	IDA IDA: 通过直接分析推断	24703694	GOA
part of mitochondrial ribonuclease P complex	IPI IPI: 通过物理相互作用推断	29880640	GOA
located in mitochondrion	IDA IDA: 通过直接分析推断	23042678	GOA
located in mitochondrion	IMP IMP: 通过突变表型推断	27132592	GOA
part of tRNA methyltransferase complex	IPI IPI: 通过物理相互作用推断	23042678	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRMT10C 蛋白结构

tRNA_m1G_MT

0
100
200
300
403 a.a.

蛋白主名

其他名称

tRNA methyltransferase 10 homolog C

HBV pre-S2 trans-regulated protein 2

TRMT10C 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	TRMT10C	Q7L0Y3	HSD17B10	Homo sapiens	Q99714	Anti Tag CoIP	18984158
种属内	TRMT10C	Q7L0Y3	PRORP	Homo sapiens	O15091	Anti Tag CoIP	18984158
种属内	TRMT10C	Q7L0Y3	HSD17B10	Homo sapiens	Q99714	Methyltransferase Ass	29880640

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Combined Oxidative Phosphorylation Deficiency 30

COXPD30	Combined Oxidative Phosphorylation Defect Type 30
Combined Oxidative Phosphorylation Deficiency, Type 30

Mitochondrial Disease

Mitochondrial Diseases

Mitochondrial Disorder

Combined Oxidative Phosphorylation Deficiency 6

Severe X-Linked Mitochondrial Encephalomyopathy	COXPD6
Mitochondrial Encephalomyopathy Due To Combined Oxidative Phosphorylation Defect 6	Mitochondrial Encephalomyopathy Due To Coxpd6
Encephalomyopathy, Mitochondrial, X-Linked	Encephalomyopathy Mitochondrial X-Linked
Oxidative Phosphorylation Deficiency, Combined, Type 6

Alpha-Aminoadipic And Alpha-Ketoadipic Aciduria

2-Aminoadipic 2-Oxoadipic Aciduria	Amoxad
AAKAD	2-Ketoadipic Aciduria
Alpha-Aminoadipic Aciduria	Amino Adipic Aciduria
Aciduria, 2-Aminoadipic 2-Oxoadipic

Lactic Acidosis

Acidosis, Lactic

Acidosis Lactic

Respiratory Failure

Acute Respiratory Failure	Chronic Respiratory Failure
Respiratory Insufficiency	Acute-On-Chronic Respiratory Failure
Respiratory Disease	Acute And Chronic Respiratory Failure
Respiratory Insufficiency/Failure	Chronic Respiratory Disease
Pulmonary Valve Insufficiency	Chronic Disease Of Respiratory System
Respiration Disorders	Respiratory Tract Diseases
Lung Failure Nos	Pulmonary Failure
Arf - [Acute Respiratory Failure]	Acute Respiratory Insufficiency
Acute Pulmonary Insufficiency	Acute Respiration Failure
Chronic Respiration Failure

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS15088	TRMT10C Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	TRMT10C	RGD	RGD:1306333
Macaca mulatta	TRMT10C	VGNC	VGNC:79569
Bos taurus	TRMT10C	VGNC	VGNC:36367
Mus musculus	TRMT10C	MGD	MGI:1196261
Felis catus	TRMT10C	VGNC	VGNC:66567
Canis familiaris	TRMT10C	VGNC	VGNC:47853

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TRMT10C - tRNA methyltransferase 10C, mitochondrial RNase P subunit Gene

关于 TRMT10C

功能概要

TRMT10C 基因产物(1)

TRMT10C 蛋白结构

TRMT10C 蛋白互作信息

关联疾病

直系同源

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TRMT10C - tRNA methyltransferase 10C, mitochondrial RNase P subunit Gene

关于 TRMT10C

功能概要

TRMT10C 基因产物(1)

TRMT10C 蛋白结构

TRMT10C 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z