2. Gene
  3. LRIF1 - ligand dependent nuclear receptor interacting factor 1 Gene

LRIF1 - ligand dependent nuclear receptor interacting factor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：配体依赖性核受体相互作用因子 1

种属: Homo sapiens

同用名: RIF1; FSHD3; HBiX1; C1orf103

基因 ID: 55791 | 基因类型: protein coding

关于 LRIF1

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:110,874,957-110,963,922 (from NCBI)

This gene has 3 transcripts (splice variants), 170 orthologues and is associated with 1 phenotype. Broad expression in testis (RPKM 11.6), ovary (RPKM 5.5) and 24 other tissues.

功能概要

预测可启用视黄酸受体结合活性。通过 X 染色体的失活参与剂量补偿。位于巴尔体；中心卫星；和核质。与染色体、端粒区域共定位。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable retinoic acid receptor binding activity. Involved in dosage compensation by inactivation of X chromosome. Located in Barr body; centriolar satellite; and nucleoplasm. Colocalizes with chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022]

LRIF1 基因产物(2)

mRNA Protein Name
NM_001006945.2 NP_001006946.1 ligand-dependent nuclear receptor-interacting factor 1 isoform 2
NM_018372.4 NP_060842.3 ligand-dependent nuclear receptor-interacting factor 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15383276 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dosage compensation by inactivation of X chromosome IMP
IMP: 通过突变表型推断
23542155 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Barr body IDA
IDA: 通过直接分析推断
23542155 GOA
colocalizes with chromosome, telomeric region IDA
IDA: 通过直接分析推断
24270157 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ligand-dependent nuclear receptor-interacting factor 1

HP1-binding protein enriched in inactive X chromosome protein 1

LRIF1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
LRIF1 Q5T3J3 ZBTB14 Homo sapiens O43829
Y2H Array
32814053
种属内
LRIF1 Q5T3J3 ZBTB14 Homo sapiens O43829
Y2H Pooling
32814053
种属内
LRIF1 Q5T3J3 ZBTB14 Homo sapiens O43829
Validated Y2H
32814053
种属内
LRIF1 Q5T3J3 SPATA18 Homo sapiens Q8TC71
Validated Y2H
32296183
种属内
LRIF1 Q5T3J3 BANP Homo sapiens Q8N9N5-2
Y2H Array
32296183
种属内
LRIF1 Q5T3J3 BANP Homo sapiens Q8N9N5-2
Y2H Prey Pooling
32296183
种属内
LRIF1 Q5T3J3 BANP Homo sapiens Q8N9N5-2
Validated Y2H
32296183
种属内
LRIF1 Q5T3J3 ZNF410 Homo sapiens Q86VK4-3
Validated Y2H
32296183
种属内
LRIF1 Q5T3J3 SLC3A2 Homo sapiens P08195-4
Y2H Array
32814053
种属内
LRIF1 Q5T3J3 SLC3A2 Homo sapiens P08195-4
Y2H Pooling
32814053
种属内
LRIF1 Q5T3J3 SLC3A2 Homo sapiens P08195-4
Validated Y2H
32814053
种属内
LRIF1 Q5T3J3 SMCHD1 Homo sapiens A6NHR9
Anti Bait CoIP
23542155
种属内
LRIF1 Q5T3J3 SMCHD1 Homo sapiens A6NHR9
Anti Tag CoIP
26496610
种属内
LRIF1 Q5T3J3 SMCHD1 Homo sapiens A6NHR9
Anti Tag CoIP
23542155
种属内
LRIF1 Q5T3J3 TSEN15 Homo sapiens Q8WW01
Validated Y2H
32296183
种属内
LRIF1 Q5T3J3 FOXD4L6 Homo sapiens Q3SYB3
Validated Y2H
32814053
种属内
LRIF1 Q5T3J3 FOXD4L6 Homo sapiens Q3SYB3
Y2H Array
32814053
种属内
LRIF1 Q5T3J3 FOXD4L6 Homo sapiens Q3SYB3
Y2H Pooling
32814053
种属内
LRIF1 Q5T3J3 VSX2 Homo sapiens P58304
Validated Y2H
32814053
种属内
LRIF1 Q5T3J3 VSX2 Homo sapiens P58304
Y2H Array
32814053
种属内
LRIF1 Q5T3J3 VSX2 Homo sapiens P58304
Y2H Pooling
32814053
种属内
LRIF1 Q5T3J3 CRACR2A Homo sapiens Q9BSW2
Validated Y2H
32296183
种属内
LRIF1 Q5T3J3 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
种属内
LRIF1 Q5T3J3 CBX3 Homo sapiens Q13185
Y2H Prey Pooling
32296183
种属内
LRIF1 Q5T3J3 CBX3 Homo sapiens Q13185
Y2H Array
32296183
种属内
LRIF1 Q5T3J3 CBX3 Homo sapiens Q13185
Anti Tag CoIP
23542155
种属内
LRIF1 Q5T3J3 CBX5 Homo sapiens P45973
Anti Tag CoIP
23542155
种属内
LRIF1 Q5T3J3 CBX5 Homo sapiens P45973
Y2H
23542155
种属内
LRIF1 Q5T3J3 CBX5 Homo sapiens P45973
Y2H
21900206
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Facioscapulohumeral Muscular Dystrophy 3, Digenic

FSHD3
Facioscapulohumeral Muscular Dystrophy 2, Digenic

Facioscapulohumeral Muscular Dystrophy 2

FSHD2

Fshd1b

Facioscapulohumeral Muscular Dystrophy 1b

Fshd2, Digenic

Muscular Dystrophy, Facioscapulohumeral, Type 2

Muscular Dystrophy, Facioscapulohumeral, Type 1b

Fascioscapulohumeral Muscular Dystrophy 2, Digenic

Facioscapulohumeral Muscular Dystrophy Type 2

Digenic Facioscapulohumeral Muscular Dystrophy

Digenic Fshd2

Facioscapulohumeral Muscular Dystrophy Type 1b

Dystrophy, Muscular, Facioscapulohumeral, Type 2
Facioscapulohumeral Muscular Dystrophy 1

Facioscapulohumeral Muscular Dystrophy

Fshd

Landouzy-Dejerine Muscular Dystrophy

Muscular Dystrophy, Facioscapulohumeral

FSHD1

Fshd1a

Muscular Dystrophy, Facioscapulohumeral, Type 1a

Facioscapulohumeral Muscular Dystrophy Type 1a

Fsh Muscular Dystrophy

Facioscapulohumeral Muscular Dystrophy 1a

Facioscapulohumeral Atrophy

Facioscapulohumeral Myopathy

Muscular Dystrophy, Facioscapulohumeral, Type 1

Facioscapulohumeral Muscular Dystrophy Type 1

Landouzy Dejerine Muscular Dystrophy

Muscular Dystrophy, Landouzy-Dejerine

Fshmd1a

Facio-Scapulo-Humeral Dystrophy

Facioscapulohumeral Type Progressive Muscular Dystrophy

Facioscapuloperoneal Muscular Dystrophy

Facioscapulohumeral Dystrophy

Fsh Dystrophy

Landouzy-Dejerine Dystrophy

Landouzy-Dejerine Myopathy

Fmd

Facioscapulohumeral Muscular Dystrophy-1a

Muscular Dystrophy Facioscapulohumeral

Dystrophy, Muscular, Facioscapulohumeral

Dystrophy, Muscular, Facioscapulohumeral, Type 1

Landouzy-Dejerine Disease

Landouzy-Déjerine Atrophy

Facioscapulohumeral Muscle Dystrophy

Fmd - [Facioscapulohumeral Muscular Dystrophy]

Fsh - [Facioscapulohumeral Muscular Dystrophy]

Fshd - [Facioscapulohumeral Muscular Dystrophy]

Landouzy-Déjerine Dystrophy Or Facioscapulohumeral Atrophy

Landouzy-Déjérine Muscular Dystrophy
Digenic Disease
Muscular Dystrophy

Muscular Dystrophies

Congenital Md

Congenital Muscular Dystrophy

Cmd

Mdc

Dystrophy, Muscular

Gower'S Muscular Dystrophy

Progressive Musclular Dystrophy

Pseudohypertrophic Atrophy

Pseudohypertrophic Muscle Paralysis

Pseudohypertrophic Muscular Atrophy

Pseudohypertrophic Muscular Dystrophy

Pseudohypertrophic Paralysis

Pseudomuscular Hypertrophy
Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome

Icf Syndrome

Immunodeficiency Syndrome, Variable

Ciid

Centromeric Instability, Immunodeficiency Syndrome

Immune Deficiency, Variable, With Centromeric Instability Of Chromosomes 1, 9, And 16

Icf
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07786 LRIF1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus LRIF1 MGD MGI:2445214
Bos taurus LRIF1 VGNC VGNC:30981
Rattus norvegicus LRIF1 RGD RGD:1306520
Felis catus LRIF1 VGNC VGNC:63280
Macaca mulatta LRIF1 VGNC VGNC:74406
Canis familiaris LRIF1 VGNC VGNC:42766
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