1. Gene
  2. YLPM1 - YLP motif containing 1 Gene

YLPM1 - YLP motif containing 1 Gene

中文名称:含 YLP 基序 1

种属: Homo sapiens

同用名: ZAP3; ZAP113; PPP1R169; C14orf170

基因 ID: 56252 | 基因类型: protein coding

关于 YLPM1

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:74,763,316-74,837,318 (from NCBI)

This gene has 9 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in testis (RPKM 14.0), brain (RPKM 9.5) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计参与端粒维护的调节。预计在 RNA 聚合酶 II 的转录负调节上游或负调节内起作用。位于胞质溶胶和核斑点。 [由基因组资源联盟提供,2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in regulation of telomere maintenance. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

YLPM1 基因产物(2)

mRNA Protein Name
NM_001411052.1 NP_001397981.1 YLP motif-containing protein 1 isoform 2
NM_019589.3 NP_062535.2 YLP motif-containing protein 1 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21078624 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17890166 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

YLPM1 蛋白结构

AAA_33

AAA_33: AAA domain (1836 - 1976)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2146 a.a.
蛋白主名 其他名称

YLP motif-containing protein 1

nuclear protein ZAP3

YLPM1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
YLPM1 P49750 CACNA1A Homo sapiens O00555
Y2H
21078624
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Ceroid Lipofuscinosis, Neuronal, 6a

Neuronal Ceroid Lipofuscinosis 6

CLN6

Vlincl

Cln6 Disease

Ceroid Lipofuscinosis, Neuronal, 6

Late-Infantile Neuronal Ceroid Lipofuscinosis

CLN6A

Neuronal Ceroid Lipofuscinosis, Late Infantile, Variant

Neuronal Ceroid Lipofuscinosis 6a

Neuronal Ceroid Lipofuscinosis 6 Variable Age Of Onset

Cln6 Disease, Adult Kufs Type A

Cln6 Disease, Late Infantile

Neuronal Ceroid Lipofuscinosis, Gypsy/Indian Early Juvenile Variant

Ceroid Lipofuscinosis Neuronal 6

Cln6-Related Neuronal Ceroid Lipofuscinosis

Late Infantile Neuronal Ceroid Lipofuscinosis

Jansky-Bielschowsky Disease

Lincl

Late Infantile Ncl

Neuronal Ceroid Lipofuscinosis 6 With Variable Age At Onset

Variant Late-Onset Infantile Neuronal Ceroid Lipofuscinosis

Ceroid Lipofuscinosis, Neuronal, Late Infantile, Variant

Lipofuscinosis, Ceroid, Neuronal, Type 6

Ceroid Lipofuscinosis, Neuronal, 5

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus YLPM1 VGNC VGNC:37031
Mus musculus YLPM1 MGD MGI:1926195
Canis familiaris YLPM1 VGNC VGNC:48494
Macaca mulatta YLPM1 VGNC VGNC:79092
Rattus norvegicus YLPM1 RGD RGD:1564946