2. Gene
  3. ERGIC1 - endoplasmic reticulum-golgi intermediate compartment 1 Gene

ERGIC1 - endoplasmic reticulum-golgi intermediate compartment 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：内质网-高尔基中间室 1

种属: Homo sapiens

同用名: AMC2; AMCN; NET24; ERGIC32; ERGIC-32

基因 ID: 57222 | 基因类型: protein coding

关于 ERGIC1

Cytogenetic location: 5q35.1 Genomic coordinates (GRCh38): 5:172,834,251-172,952,683 (from NCBI)

This gene has 30 transcripts (splice variants), 200 orthologues, 2 paralogues and is associated with 2 phenotypes. Ubiquitous expression in prostate (RPKM 69.0), adrenal (RPKM 49.7) and 25 other tissues.

功能概要

该基因编码一种循环膜蛋白，它是一种内质网-高尔基体中间室 (ERGIC) 蛋白，它与该蛋白家族的其他成员相互作用以增加它们的周转率。[RefSeq 提供，2008 年 7 月]

This gene encodes a cycling membrane protein which is an endoplasmic reticulum-golgi intermediate compartment (ERGIC) protein which interacts with Other members of this protein family to increase their turnover. [provided by RefSeq, Jul 2008]

ERGIC1 基因产物(1)

mRNA Protein Name
NM_001031711.3 NP_001026881.1 endoplasmic reticulum-Golgi intermediate compartment protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15308636 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endoplasmic reticulum to Golgi vesicle-mediated transport IDA
IDA: 通过直接分析推断
15308636 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: 通过直接分析推断
15308636 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ERGIC1 蛋白结构

ERGIC_N

ERGIC_N: Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) (5 - 98)

COPIIcoated_ERV

COPIIcoated_ERV: Endoplasmic reticulum vesicle transporter (106 - 271)

  • 0
  • 100
  • 200
  • 290 a.a.
蛋白主名 其他名称

endoplasmic reticulum-Golgi intermediate compartment protein 1

ER-Golgi intermediate compartment 32 kDa protein

ERGIC1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ERGIC1 Q969X5 ERGIC3 Homo sapiens Q9Y282
Crosslink
15308636
种属内
ERGIC1 Q969X5 ERGIC3 Homo sapiens Q9Y282
IF
15308636
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Arthrogryposis Multiplex Congenita 2, Neurogenic Type

Arthrogryposis Multiplex Congenita, Neurogenic Type

Amcn

Arthrogryposis Multiplex Congenita Neurogenic Type

AMC2

Amc, Neurogenic Type

Neurogenic-Type Arthrogryposis Multiplex Congenita-2

Amc Neurogenic Type

Neurogenic Type Of Amc

Neurogenic Arthrogryposis Multiplex Congenita

Arthrogryposis Multiplex Congenita, Neurogenic
Distal Arthrogryposis

Arthrogryposis Multiplex Congenita

Arthrogryposis

Congenital Multiple Arthrogryposis

Congenital Arthromyodysplasia

Fibrous Ankylosis Of Multiple Joints

Guerin-Stern Syndrome

Guérin-Stern Syndrome

Myodystrophia Fetalis Deformans

Otto Syndrome

Rocher-Sheldon Syndrome

Rossi Syndrome

Amc

Multiple Congenital Arthrogryposis

Arthrogryposis Syndrome

Arthrogryposis, Distal

Distal Arthrogryposis Syndrome

Freeman-Sheldon Syndrome

Arthrogryposis, Distal, Type 2b

Congenital Multiplex Arthrogryposis

Amyoplasia Congenita

Congenital Amyoplasia

Amc - [Arthrogryposis Multiplex Congenita]
Frank-Ter Haar Syndrome

Ter Haar Syndrome

Borrone Dermatocardioskeletal Syndrome

FTHS

Autosomal Recessive Melnick-Needles Syndrome

Borrone Di Rocco Crovato Syndrome

Megalocornea, Multiple Skeletal Anomalies, And Developmental Delay

Melnick-Needles Syndrome, Autosomal Recessive, Formerly

Frank Ter Haar Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04493 ERGIC1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ERGIC1 MGD MGI:1914708
Rattus norvegicus ERGIC1 RGD RGD:1585015
Macaca mulatta ERGIC1 VGNC VGNC:82141
Felis catus ERGIC1 VGNC VGNC:61939
Bos taurus ERGIC1 VGNC VGNC:28578
Canis familiaris ERGIC1 VGNC VGNC:40450
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