SLAMF7 - SLAM family member 7 Gene

中文名称：SLAM 家族成员 7

种属: Homo sapiens

同用名: 19A; CS1; CD319; CRACC

基因 ID: 57823 | 基因类型: protein coding

关于 SLAMF7

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:160,739,057-160,754,821 (from NCBI)

This gene has 11 transcripts (splice variants), 138 orthologues and 9 paralogues. Biased expression in lymph node (RPKM 22.3), appendix (RPKM 19.3) and 13 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与适应性免疫反应。预计在自然杀伤细胞激活的调节上游或调节内起作用。位于内质网。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in adaptive immune response. Predicted to act upstream of or within regulation of natural killer cell activation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

SLAMF7 基因产物(10)

mRNA	Protein	Name
NM_001282588.2	NP_001269517.1	SLAM family member 7 isoform b precursor
NM_001282589.2	NP_001269518.1	SLAM family member 7 isoform c precursor
NM_001282590.2	NP_001269519.1	SLAM family member 7 isoform d
NM_001282591.2	NP_001269520.1	SLAM family member 7 isoform e
NM_001282592.2	NP_001269521.1	SLAM family member 7 isoform f precursor
NM_001282593.2	NP_001269522.1	SLAM family member 7 isoform g
NM_001282594.2	NP_001269523.1	SLAM family member 7 isoform h
NM_001282595.1	NP_001269524.1	SLAM family member 7 isoform i
NM_001282596.2	NP_001269525.1	SLAM family member 7 isoform j
NM_021181.5	NP_067004.3	SLAM family member 7 isoform a precursor

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables identical protein binding	IPI IPI: 通过物理相互作用推断	15153464	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLAMF7 蛋白结构

V-set

Ig_3

0
100
200
300
335 a.a.

蛋白主名

其他名称

SLAM family member 7

19A24 protein

SLAMF7 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	SLAMF7	Q9NQ25	SLAMF7	Homo sapiens	Q9NQ25	FACS	15153464
种属内	SLAMF7	Q9NQ25	MAK	Homo sapiens	P20794	Y2H Array	21988832
种属内	SLAMF7	Q9NQ25	CMTM6	Homo sapiens	Q9NX76	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	PTCD2	Homo sapiens	Q8WV60	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	SLAMF7	Homo sapiens	Q9NQ25	Protein Array	21982860
种属内	SLAMF7	Q9NQ25	NCR3	Homo sapiens	O14931	FACS	15153464
种属内	SLAMF7	Q9NQ25	SH2D1B	Homo sapiens	O14796	SPR	24642916
种属内	SLAMF7	Q9NQ25	TBC1D23	Homo sapiens	Q9NUY8	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	CLK3	Homo sapiens	P49761	Y2H Array	21988832
种属内	SLAMF7	Q9NQ25	HUS1	Homo sapiens	O60921	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	TNFSF9	Homo sapiens	P41273	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	CTNNB1	Homo sapiens	P35222	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	YIF1A	Homo sapiens	O95070	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	FBXO2	Homo sapiens	Q9UK22	Anti Tag CoIP	33961781
种属内	SLAMF7	Q9NQ25	SH2D1A	Homo sapiens	O60880	SPR	24642916
种属内	SLAMF7	Q9NQ25	NAGPA	Homo sapiens	Q9UK23	Anti Tag CoIP	33961781

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 SLAMF7 蛋白

目录号	产品名	蛋白编号	纯度
HY-P72416	CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His-Avi)	Q9NQ25-1 (S23-M226)	≥95%
HY-P72460	CRACC/SLAMF7 Protein, Human (HEK293, His)	Q9NQ25-1 (S23-M226)	≥95%
HY-P77202	CRACC/SLAMF7 Protein, Human (HEK293, hFc)	Q9NQ25-1 (S23-M226)	≥95%
HY-P77203	CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, Fc)	Q9NQ25-1 (S23-M226)	≥95%
HY-P77205	CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His)	Q9NQ25-1 (S23-M226)	≥95%
HY-P78517	CRACC/SLAMF7 Protein, Human (HEK293, mFc)	Q9NQ25-1 (S23-M226)	≥95%
HY-P78518	CRACC/SLAMF7 Protein, Human (HEK293, His-Avi)	Q9NQ25-1 (S23-M226)	≥95%

SLAMF7 抗体

目录号	产品名	应用	反应物种
HY-P81432	SLAMF7/CS1 Antibody (YA1177)	IHC-P	Human
HY-P81747	CS1 Antibody (YA1492)	FC, ELISA	Human

关联疾病

疾病名称

别名

Plasmablastic Lymphoma

Pbl	Immunoblastic Large-Cell Lymphoma

Smoldering Myeloma

Lupus Erythematosus

Lupus	Lupus Vulgaris
Lupus Erythematosus, Discoid	Lupus Erythematosus, Systemic
Subacute Cutaneous Lupus	Le - [Lupus Erythematosus]

Intellectual Developmental Disorder, Autosomal Dominant 10

MRD10	Mental Retardation, Autosomal Dominant 10
Autosomal Dominant Non-Syndromic Intellectual Disability 10	Autosomal Dominant Intellectual Developmental Disorder 10
Autosomal Dominant Mental Retardation 10	Mental Retardation, Autosomal Dominant, Type 10

Systemic Lupus Erythematosus

Lupus Nephritis	SLE
Disseminated Lupus Erythematosus	Systemic Lupus Erythematosus, Susceptibility To
Lupus Erythematosus, Systemic	Lupus Nephritis, Susceptibility To
Libman-Sacks Disease	Systemic Lupus Erythematosus Susceptibility To
Sle - Lupus Erythematosus, Systemic	Le Syndrome
Lupus	Lupus Erythematosus Systemic
Lupus Erythematosus, Systemic, Susceptibility To	Lupus Vulgaris
Lupus Erythematosus, Discoid	Lupus Erythematosus
Systemic Lupus Erythematosus Nos	Sle - [Systemic Lupus Erythematosus]

Monoclonal Gammopathy Of Uncertain Significance

Monoclonal Gammopathy Of Undetermined Significance	Mgus
Mgus - [Monoclonal Gammopathy Of Undetermined Significance]	Monoclonal Gammopathy Nos
Iga Gammopathy	Monoclonal Gammoglobulinopathy

Igg4-Related Disease

Multifocal Fibrosclerosis	Igg4-Related Sclerosing Disease
Igg4-Related Systemic Disease	Immunoglobulin G4-Related Sclerosing Disease
Hyper-Igg4 Disease	Igg4-Associated Disease
Igg4-Positive Multiorgan Lymphoproliferative Syndrome	Igg4-Related Autoimmune Disease
Igg4-Related Systemic Sclerosing Disease	Igg4-Syndrome
Multifocal Idiopathic Fibrosclerosis	Systemic Igg4-Related Plasmacytic Syndrome
Systemic Igg4-Related Sclerosing Syndrome	Mediastinal Fibrosis, Familial
Retroperitoneal Fibrosis, Familial	Igg4-Rd

Non-Secretory Myeloma

Blood Protein Disease

Blood Protein Disorders

Blood Protein Disorder

Plasma Cell Leukemia

Plasma Cell Leukaemia	Leukemia, Plasma Cell
Plasmacytic Leukaemia	Plasmacytic Leukemia
Pcl	Plasma Cell Leukaemia, Nos
Leukemic Plasma Cell	Plasma Cell Leukaemia Without Mention Of Remission

Bone Marrow Cancer

Malignant Neoplasm Of Bone Marrow	Bone Marrow Neoplasm
Bone Marrow Tumor	Malignant Bone Marrow Tumor
Myeloproliferative Disorders	Bone Marrow Neoplasms
Myeloproliferative Disease	Chronic Myeloproliferative Disorder

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

目录号	产品名	作用方式	纯度	Phase
HY-P99454	Azintuxizumab vedotin		98.55%	Phase 1

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12981	SLAMF7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-P99453	Azintuxizumab		≥99.0%	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	SLAMF7	VGNC	VGNC:34655
Canis familiaris	SLAMF7	VGNC	VGNC:46208
Mus musculus	SLAMF7	MGD	MGI:1922595
Macaca mulatta	SLAMF7	VGNC	VGNC:77547
Rattus norvegicus	SLAMF7	RGD	RGD:1560190
Felis catus	SLAMF7	VGNC	VGNC:107940
Macaca fascicularis	SLAMF7	NCBI	NCBI:102133710
Others	SLAMF7	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SLAMF7 - SLAM family member 7 Gene

关于 SLAMF7

功能概要

SLAMF7 基因产物(10)

SLAMF7 蛋白结构

SLAMF7 蛋白互作信息

重组 SLAMF7 蛋白

SLAMF7 抗体

关联疾病

直系同源

热门区域

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SLAMF7 - SLAM family member 7 Gene

关于 SLAMF7

功能概要

SLAMF7 基因产物(10)

SLAMF7 蛋白结构

SLAMF7 蛋白互作信息

重组 SLAMF7 蛋白

SLAMF7 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z