2. Gene
  3. Trpm7 - transient receptor potential cation channel, subfamily M, member 7 Gene

Trpm7 - transient receptor potential cation channel, subfamily M, member 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CHAK; CHAK1; Ltpr7; Ltrpc7; LTrpC-7; TRPPLIK; 2310022G15Rik; 4833414K03Rik; 5033407O22Rik

基因 ID: 58800 | 基因类型: protein coding

关于 Trpm7

功能概要

Enables Calcium Channel activity; cytoskeletal protein binding activity; and kinase activity. Acts upstream of or within several processes, including calcium ion transport; calcium-dependent cell-matrix adhesion; and protein autophosphorylation. Located in plasma membrane and ruffle. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and skin. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1. Orthologous to human TRPM7 (transient receptor potential cation channel subfamily M member 7). [provided by Alliance of Genome Resources, Apr 2022]

Trpm7 基因产物(2)

mRNA Protein Name
NM_001164325.1 NP_001157797.1 transient receptor potential cation channel subfamily M member 7 isoform 2
NM_021450.2 NP_067425.2 transient receptor potential cation channel subfamily M member 7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
16407977 MGI
enables calcium channel activity IDA
IDA: 通过直接分析推断
16407977 MGI
enables kinase activity IDA
IDA: 通过直接分析推断
16407977 MGI
enables myosin binding IPI
IPI: 通过物理相互作用推断
16407977 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16407977 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
29203869 MGI
enables zinc ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
28696294 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actomyosin structure organization IDA
IDA: 通过直接分析推断
16407977 MGI
acts upstream of or within calcium ion transport IDA
IDA: 通过直接分析推断
16407977 MGI
acts upstream of or within calcium-dependent cell-matrix adhesion IDA
IDA: 通过直接分析推断
16407977 MGI
involved in intracellular magnesium ion homeostasis IMP
IMP: 通过突变表型推断
21045827 MGI
involved in magnesium ion transmembrane transport IDA
IDA: 通过直接分析推断
11385574 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
16407977 MGI
involved in protein homotetramerization IDA
IDA: 通过直接分析推断
30108148 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
16407977 MGI
involved in zinc ion transport IDA
IDA: 通过直接分析推断
28696294 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
28696294 MGI
located in nucleus IDA
IDA: 通过直接分析推断
24855944 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16407977 MGI
located in ruffle IDA
IDA: 通过直接分析推断
16407977 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transient receptor potential cation channel subfamily M member 7

channel-kinase 1

long transient receptor potential channel 7

transient receptor potential M7

transient receptor potential-phospholipase C-interacting kinase

transient receptor potential-related protein, ChaK

Trpm7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Trpm7 Q923J1 Ddb1 Mus musculus Q3U1J4
Anti Tag CoIP
24855944
种属间
Trpm7 Q923J1 DDX3X Homo sapiens O00571
Anti Bait CoIP
24855944
种属内
Trpm7 Q923J1 Actb Mus musculus P60710
Anti Tag CoIP
16407977
种属内
Trpm7 Q923J1 Actb Mus musculus P60710
Anti Tag CoIP
24855944
种属内
Trpm7 Q923J1 Myh9 Mus musculus Q8VDD5
Anti Tag CoIP
16407977
种属内
Trpm7 Q923J1 Myh9 Mus musculus Q8VDD5
Protein Kinase Assay
16407977
种属内
Trpm7 Q923J1 Myh9 Mus musculus Q8VDD5
Anti Tag CoIP
24855944
种属间
Trpm7 Q923J1 RYBP Homo sapiens Q8N488
Pull Down
24855944
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101302 Naltriben mesylate 99.65% 否
HY-157227 VPC01091.4 Inhibitor 98.04% 否
HY-RS15117 TRPM7 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-133717 Naltriben / 否
HY-149999 Xeniafaraunol A Inhibitor / 否
HY-160509 BTB 06061 Inhibitor / 否
HY-162968 MRTF-A-IN-1 Inhibitor / 否
HY-162969 MRTF-A-IN-2 Inhibitor / 否
HY-168608 TRPM7-IN-1 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trpm7 NCBI NCBI:54822
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