Prmt1 - protein arginine methyltransferase 1 Gene

中文名称：蛋白质精氨酸甲基转移酶1

种属: Rattus norvegicus

同用名: Hrmt1l2

关于 Prmt1

功能概要

实现相同的蛋白质结合活性；蛋白质-精氨酸 N-甲基转移酶活性；和 snoRNP 结合活性。参与多个过程，包括肝再生；红细胞分化的正调节；和血红蛋白生物合成过程的积极调节。作用于肽基-精氨酸甲基化的上游或内部，形成不对称-二甲基精氨酸。位于胞质溶胶中；膜;和核。部分含蛋白质复合物。哮喘的生物标志物。与人类 PRMT1（蛋白质精氨酸甲基转移酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity; protein-arginine N-methyltransferase activity; and snoRNP binding activity. Involved in several processes, including liver regeneration; positive regulation of erythrocyte differentiation; and positive regulation of hemoglobin biosynthetic process. Acts upstream of or within peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. Located in cytosol; membrane; and nucleus. Part of protein-containing complex. Biomarker of asthma. Orthologous to human PRMT1 (protein arginine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]