2. Gene
  3. Rtn4r - reticulon 4 receptor Gene

Rtn4r - reticulon 4 receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NgR; NgR1; NOGOR

基因 ID: 65079 | 基因类型: protein coding

关于 Rtn4r

功能概要

Enables chondroitin sulfate binding activity; heparin binding activity; and neuregulin receptor activity. Involved in several processes, including corpus callosum development; negative regulation of neuron projection development; and neuronal signal transduction. Acts upstream of or within axonogenesis. Located in several cellular components, including axonal growth cone; dendritic shaft; and neuronal cell body. Is integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; forelimb bud; intestine; male reproductive gland or organ; and nervous system. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human RTN4R (reticulon 4 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Rtn4r 基因产物(1)

mRNA Protein Name
NM_022982.3 NP_075358.1 reticulon-4 receptor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chondroitin sulfate binding IDA
IDA: 通过直接分析推断
22406547 MGI
enables heparin binding IDA
IDA: 通过直接分析推断
22406547 MGI
enables neuregulin receptor activity IDA
IDA: 通过直接分析推断
22923615 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11201742 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axonogenesis IDA
IDA: 通过直接分析推断
11201742 MGI
involved in corpus callosum development IMP
IMP: 通过突变表型推断
27339102 MGI
involved in negative regulation of axon extension IDA
IDA: 通过直接分析推断
22923615 MGI
involved in negative regulation of axon regeneration IMP
IMP: 通过突变表型推断
22406547 MGI
involved in negative regulation of neuron projection development IMP
IMP: 通过突变表型推断
15504325 MGI
involved in neuronal signal transduction IDA
IDA: 通过直接分析推断
22923615 MGI
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
22923615 MGI
involved in regulation of postsynapse assembly EXP
EXP: 通过实验结果推断
26748478 MGI
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
26748478 MGI
involved in regulation of synapse assembly IDA
IDA: 通过直接分析推断
26838771 MGI
involved in regulation of synapse assembly IMP
IMP: 通过突变表型推断
26838771 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axonal growth cone IDA
IDA: 通过直接分析推断
22923615 MGI
located in cell surface IDA
IDA: 通过直接分析推断
22325200 MGI
located in dendritic shaft IDA
IDA: 通过直接分析推断
22325200 MGI
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
26748478 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
26748478 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
26838771 MGI
located in growth cone IDA
IDA: 通过直接分析推断
21817055 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
22923615 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
22923615 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11201742 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

reticulon-4 receptor

nogo66 receptor-1

重组 Rtn4r 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71158 Nogo Receptor/NgR Protein, Mouse (HEK293, His) Q99PI8 (C27-S447) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12334 RTN4R Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rtn4r NCBI NCBI:65078
Macaca fascicularis Rtn4r NCBI NCBI:102139327
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