SRP68 - signal recognition particle 68 Gene

中文名称：信号识别粒子 68

种属: Homo sapiens

关于 SRP68

功能概要

该基因编码信号识别粒子 (SRP) 的一个亚基。 SRP 是一种核糖核蛋白复合物，可将分泌蛋白和膜蛋白转运至内质网进行加工。该复合物包括一个 7S RNA 和六个蛋白质亚基。编码的蛋白质是 SRP 的 68kDa 组分，并与 SRP 功能所需的 72kDa 亚基形成异二聚体。已观察到该基因编码多种亚型的选择性剪接转录变体，该基因的三个假基因位于 17 号染色体上的 Smith-Magenis 综合征区域内。[RefSeq 提供，2012 年 5 月]

This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, May 2012]