2. Gene
  3. ZNF3 - zinc finger protein 3 Gene

ZNF3 - zinc finger protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 3

种属: Homo sapiens

同用名: A8-51; HF.12; KOX25; PP838; Zfp113

基因 ID: 7551 | 基因类型: protein coding

关于 ZNF3

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,063,837-100,082,577 (from NCBI)

This gene has 15 transcripts (splice variants), 178 orthologues and 174 paralogues. Ubiquitous expression in endometrium (RPKM 7.6), thyroid (RPKM 6.8) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与 RNA 聚合酶 II 对转录的负调控。预测位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF3 基因产物(22)

mRNA Protein Name
NM_001278284.2 NP_001265213.1 zinc finger protein 3 isoform 2
NM_001278287.2 NP_001265216.1 zinc finger protein 3 isoform 2
NM_001278290.2 NP_001265219.1 zinc finger protein 3 isoform 2
NM_001278291.2 NP_001265220.1 zinc finger protein 3 isoform 3
NM_001278292.2 NP_001265221.1 zinc finger protein 3 isoform 3
NM_001318135.2 NP_001305064.1 zinc finger protein 3 isoform 2
NM_001318136.2 NP_001305065.1 zinc finger protein 3 isoform 4
NM_001318137.2 NP_001305066.1 zinc finger protein 3 isoform 5
NM_001362775.2 NP_001349704.1 zinc finger protein 3 isoform 4
NM_001362776.2 NP_001349705.1 zinc finger protein 3 isoform 6
NM_001362777.2 NP_001349706.1 zinc finger protein 3 isoform 3
NM_001371210.1 NP_001358139.1 zinc finger protein 3 isoform 1
NM_001371211.1 NP_001358140.1 zinc finger protein 3 isoform 2
NM_001371212.1 NP_001358141.1 zinc finger protein 3 isoform 2
NM_001371213.1 NP_001358142.1 zinc finger protein 3 isoform 2
NM_001371214.1 NP_001358143.1 zinc finger protein 3 isoform 2
NM_001371215.1 NP_001358144.1 zinc finger protein 3 isoform 3
NM_001371216.1 NP_001358145.1 zinc finger protein 3 isoform 3
NM_001371217.1 NP_001358146.1 zinc finger protein 3 isoform 4
NM_001371218.1 NP_001358147.1 zinc finger protein 3 isoform 7
NM_017715.4 NP_060185.2 zinc finger protein 3 isoform 1
NM_032924.5 NP_116313.3 zinc finger protein 3 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
18255255 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
18255255 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZNF3 蛋白结构

KRAB

KRAB: KRAB box (51 - 91)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (215 - 238)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (243 - 266)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (273 - 294)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (299 - 323)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (330 - 350)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (354 - 379)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (383 - 406)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 446 a.a.
蛋白主名 其他名称

zinc finger protein 3

C2-H2 type zinc finger protein

ZNF3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZNF3 P17036 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra ZNF3 P17036 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra ZNF3 P17036 ZNF212 Homo sapiens Q9UDV6
Y2H
18255255
Intra ZNF3 P17036 ZNF212 Homo sapiens Q9UDV6
Pull Down
18255255
Intra ZNF3 P17036 GOLGA2 Homo sapiens Q08379
Validated Y2H
32296183
Intra ZNF3 P17036 TRAF4 Homo sapiens Q9BUZ4
Y2H Array
32296183
Intra ZNF3 P17036 MCC Homo sapiens P23508
Validated Y2H
32296183
Intra ZNF3 P17036 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
25416956
Intra ZNF3 P17036 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra ZNF3 P17036 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
32296183
Intra ZNF3 P17036 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 MTUS2 Homo sapiens Q5JR59
Validated Y2H
25416956
Intra ZNF3 P17036 KRT27 Homo sapiens Q7Z3Y8
Validated Y2H
32296183
Intra ZNF3 P17036 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 TRAF4 Homo sapiens Q9BUZ4
Y2H Prey Pooling
25416956
Intra ZNF3 P17036 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra ZNF3 P17036 TRAF4 Homo sapiens Q9BUZ4
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
Intra ZNF3 P17036 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 MCC Homo sapiens P23508
Y2H Array
32296183
Intra ZNF3 P17036 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
25416956
Intra ZNF3 P17036 SSX2IP Homo sapiens Q9Y2D8
Validated Y2H
25416956
Intra ZNF3 P17036 SF3B4 Homo sapiens Q15427
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 SF3B4 Homo sapiens Q15427
Validated Y2H
32296183
Intra ZNF3 P17036 SF3B4 Homo sapiens Q15427
Y2H Array
32296183
Intra ZNF3 P17036 YJU2B Homo sapiens P13994
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 YJU2B Homo sapiens P13994
Y2H Array
32296183
Intra ZNF3 P17036 NDEL1 Homo sapiens Q9GZM8
Y2H Prey Pooling
32296183
Intra ZNF3 P17036 NDEL1 Homo sapiens Q9GZM8
Validated Y2H
32296183
Intra ZNF3 P17036 NDEL1 Homo sapiens Q9GZM8
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16123 ZNF3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ZNF3 MGD MGI:1929116
Rattus norvegicus ZNF3 RGD RGD:6489147
Macaca mulatta ZNF3 VGNC VGNC:81889
Bos taurus ZNF3 VGNC VGNC:37241
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