WWC2 - WW and C2 domain containing 2 Gene

中文名称：含 WW 和 C2 域 2

种属: Homo sapiens

同用名: BOMB

关于 WWC2

功能概要

该基因编码含有 WW 和 C2 结构域的蛋白质家族成员。这个家族的成员有两个 N 端 WW 结构域，介导与含有 L/PPxY 基序的靶蛋白的结合，一个用于膜结合的内部 C2 结构域，以及 C 端 α 蛋白激酶 C 结合位点和 III 类 PDZ 结构域相互作用基序。该家族的蛋白质能够形成同二聚体和异二聚体并调节河马通路信号。[RefSeq 提供，2016 年 9 月]

This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling. [provided by RefSeq, Sep 2016]