EIF3A - eukaryotic translation initiation factor 3 subunit A Gene

中文名称：真核翻译起始因子 3 亚基 A

种属: Homo sapiens

同用名: EIF3; P167; p180; p185; TIF32; EIF3S10; eIF3-p170; eIF3-theta

基因 ID: 8661 | 基因类型: protein coding

关于 EIF3A

Cytogenetic location: 10q26.11 Genomic coordinates (GRCh38): 10:119,033,670-119,080,817 (from NCBI)

This gene has 3 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in thyroid (RPKM 51.4), fat (RPKM 50.1) and 25 other tissues.

功能概要

启用 RNA 结合活性。有助于翻译起始因子活动。参与 IRES 依赖性病毒翻译启动；细胞质翻译起始复合物的形成；和病毒翻译终止-重新启动。位于胞质溶胶中；核仁;和核质。真核翻译起始因子 3 复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of cytoplasmic translation initiation complex; and viral translational termination-reinitiation. Located in cytosol; nucleolus; and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Apr 2022]

EIF3A 基因产物(1)

mRNA	Protein	Name
NM_003750.4	NP_003741.1	eukaryotic translation initiation factor 3 subunit A

EIF3A 蛋白结构

PCI

0
300
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1382 a.a.

蛋白主名

其他名称

eukaryotic translation initiation factor 3 subunit A

EIF3, p180 subunit

EIF3A 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	EIF3A	Q14152	EIF1AX	Homo sapiens	P47813	Pull Down	23623729
种属内	EIF3A	Q14152	KRT7	Homo sapiens	P08729	Y2H	11169732
种属内	EIF3A	Q14152	REL	Homo sapiens	Q04864	Validated Y2H	25416956
种属内	EIF3A	Q14152	REL	Homo sapiens	Q04864	Y2H Array	25416956
种属内	EIF3A	Q14152	REL	Homo sapiens	Q04864	Y2H Prey Pooling	25416956
种属内	EIF3A	Q14152	EIF3E	Homo sapiens	P60228	GMS	23623729
种属内	EIF3A	Q14152	EIF3E	Homo sapiens	P60228	3D-EM	23623729
种属内	EIF3A	Q14152	EIF3E	Homo sapiens	P60228	Ion Exchange Chrom	23623729
种属内	EIF3A	Q14152	EIF3E	Homo sapiens	P60228	Anti Bait CoIP	17353931
种属内	EIF3A	Q14152	EIF3E	Homo sapiens	P60228	TEM	23623729
种属内	EIF3A	Q14152	EIF3E	Homo sapiens	P60228	SLCA	18599441
种属内	EIF3A	Q14152	EIF3E	Homo sapiens	P60228	Pull Down	23623729
种属内	EIF3A	Q14152	EIF3C	Homo sapiens	Q99613	GMS	23623729
种属内	EIF3A	Q14152	EIF3C	Homo sapiens	Q99613	SLCA	18599441
种属内	EIF3A	Q14152	EIF3C	Homo sapiens	Q99613	3D-EM	23623729
种属内	EIF3A	Q14152	EIF3C	Homo sapiens	Q99613	Pull Down	23623729
种属内	EIF3A	Q14152	EIF3C	Homo sapiens	Q99613	TEM	23623729
种属内	EIF3A	Q14152	EIF3C	Homo sapiens	Q99613	Ion Exchange Chrom	23623729
种属内	EIF3A	Q14152	EIF3B	Homo sapiens	P55884	Anti Bait CoIP	11169732
种属内	EIF3A	Q14152	EIF3B	Homo sapiens	P55884	Pull Down	11169732
种属内	EIF3A	Q14152	EIF3B	Homo sapiens	P55884	Y2H	11169732
种属内	EIF3A	Q14152	EIF3B	Homo sapiens	P55884	SLCA	18599441
种属内	EIF3A	Q14152	UPF1	Homo sapiens	Q92900-2	Anti Bait CoIP	18423202
种属内	EIF3A	Q14152	EIF1	Homo sapiens	P41567	Pull Down	23623729

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Craniotubular Dysplasia, Ikegawa Type

CTDI	Craniotubular Dysplasia Ikegawa Type
Doid:0112340

Diphyllobothriasis

Diphyllobothrium Infection	Fish Tapeworm
Bothriocephalosis	Infection By Bothriocephalus
Fish Tapeworm Infection	Dibothriocephalus Anaemia
Dibothriocephaliasis	Broad Tapeworm Infection
Bothriocephaliasis	Dibothriocephalus
Intestinal Diphyllobothriasis	Diphyllobothrium Infestation
Dibothriocephalus Infestation	Bothriocephalus Infestation
Adult Diphyllobothrium Infection	Tapeworm Anaemia
Infection By Diphyllobothrium Larvae

Bardet-Biedl Syndrome

Bbs	Biedl-Bardet Syndrome

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS04257	EIF3A Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	EIF3A	RGD	RGD:1307269
Felis catus	EIF3A	VGNC	VGNC:61780
Bos taurus	EIF3A	VGNC	VGNC:28392
Canis familiaris	EIF3A	VGNC	VGNC:40268
Mus musculus	EIF3A	MGD	MGI:95301

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

EIF3A - eukaryotic translation initiation factor 3 subunit A Gene

关于 EIF3A

功能概要

EIF3A 基因产物(1)

EIF3A 蛋白结构

EIF3A 蛋白互作信息

关联疾病

直系同源

热门区域

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EIF3A - eukaryotic translation initiation factor 3 subunit A Gene

关于 EIF3A

功能概要

EIF3A 基因产物(1)

EIF3A 蛋白结构

EIF3A 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z