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  3. SH2D2A - SH2 domain containing 2A Gene

SH2D2A - SH2 domain containing 2A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 SH2 结构域 2A

种属: Homo sapiens

同用名: SCAP; TSAD; VRAP; F2771

基因 ID: 9047 | 基因类型: protein coding

关于 SH2D2A

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:156,806,243-156,816,848 (from NCBI)

This gene has 6 transcripts (splice variants), 111 orthologues and 4 paralogues. Broad expression in appendix (RPKM 5.2), lymph node (RPKM 3.5) and 17 other tissues.

功能概要

该基因编码一种被认为在 T 细胞信号转导中起作用的衔接蛋白。小鼠中的一种相关蛋白负责激活淋巴细胞特异性蛋白酪氨酸激酶，并在下游信号传导中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2010 年 3 月]

This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

SH2D2A 基因产物(5)

mRNA Protein Name
NM_001161441.2 NP_001154913.1 SH2 domain-containing protein 2A isoform 1
NM_001161442.2 NP_001154914.1 SH2 domain-containing protein 2A isoform 3
NM_001161443.2 NP_001154915.1 SH2 domain-containing protein 2A isoform 4
NM_001161444.2 NP_001154916.1 SH2 domain-containing protein 2A isoform 2
NM_003975.4 NP_003966.2 SH2 domain-containing protein 2A isoform 2

SH2D2A 蛋白结构

SH2

SH2: SH2 domain (95 - 170)

  • 0
  • 100
  • 200
  • 300
  • 389 a.a.
蛋白主名 其他名称

SH2 domain-containing protein 2A

SH2 domain protein 2A

关联疾病

疾病名称 别名
Brain Meningioma

Intracranial Meningioma
Polyradiculoneuropathy
Cerebral Meningioma

Meningioma Of Cerebrum
Multiple Sclerosis

MS

Multiple Sclerosis, Susceptibility To

Disseminated Sclerosis

Multiple Sclerosis, Disease Progression, Modifier Of

Insular Sclerosis

Multiple Sclerosis Modifier Of Disease Progression

Multiple Sclerosis, Susceptibility To 1

Multiple Sclerosis, Susceptibility To, 1

Multiple Sclerosis 1

Generalized Multiple Sclerosis

Multiple Sclerosis Variant

Multiple Sclerosis Susceptibility To

Cerebrospinal Sclerosis

Generalised Multiple Sclerosis

Ms - [Multiple Sclerosis]

Disseminated Cerebrospinal Sclerosis

Disseminated Multiple Sclerosis

Disseminated Nervous System Myelosclerosis

Multiple Cerebrospinal Sclerosis

Multiple Combined Sclerosis

Multiple Sclerosis Generalised

Disseminated Brain Sclerosis

Disseminated Spinal Sclerosis

Insular Brain Sclerosis

Miliary Brain Sclerosis

Multiple Combined Sclerosis Of Spinal Cord

Multiple Ascending Sclerosis

Multiple Brain Sclerosis

Multiple Sclerosis Of Brain Stem

Multiple Sclerosis Of The Brain Stem

Multiple Sclerosis Of Cord

Sclérose En Plaques

Plaque Sclerosis

Multiple Sclerosis Of The Spinal Cord
Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Chronic Inflammatory Demyelinating Polyneuropathy

Cidp

Polyradiculoneuropathy Chronic Inflammatory Demyelinating

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Galloway-Mowat Syndrome

Galloway Mowat Syndrome

Galloway Syndrome

Hiatal Hernia-Microcephaly-Nephrosis, Galloway Type

Microcephaly Nephrosis Syndrome

Microcephaly, Hiatal Hernia, And Nephrotic Syndrome

Nephrosis Neuronal Dysmigration Syndrome

Microcephaly-Hiatus Hernia-Nephrotic Syndrome

Nephrosis-Neuronal Dysmigration Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12823 SH2D2A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SH2D2A VGNC VGNC:46111
Rattus norvegicus SH2D2A RGD RGD:1303076
Mus musculus SH2D2A MGD MGI:1351596
Bos taurus SH2D2A VGNC VGNC:34557
Felis catus SH2D2A VGNC VGNC:65092
Macaca mulatta SH2D2A VGNC VGNC:77198
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