TENT5A - terminal nucleotidyltransferase 5A Gene

中文名称：末端核苷酸转移酶 5A

种属: Homo sapiens

同用名: OI18; XTP11; FAM46A; C6orf37

基因 ID: 55603 | 基因类型: protein coding

关于 TENT5A

Cytogenetic location: 6q14.1 Genomic coordinates (GRCh38): 6:81,745,730-81,752,681 (from NCBI)

This gene has 5 transcripts (splice variants), 283 orthologues, 3 paralogues and is associated with 2 phenotypes. Broad expression in bone marrow (RPKM 86.6), salivary gland (RPKM 24.3) and 18 other tissues.

功能概要

启用 RNA 结合活性。预计参与 mRNA 稳定化。预计在对细菌的反应上游或反应内起作用。与肺非小细胞癌有关；骨关节炎;和成骨不全症 18 型。[由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in mRNA stabilization. Predicted to act upstream of or within response to bacterium. Implicated in lung non-small cell carcinoma; osteoarthritis; and osteogenesis imperfecta type 18. [provided by Alliance of Genome Resources, Apr 2022]

TENT5A 基因产物(1)

mRNA	Protein	Name
NM_017633.3	NP_060103.2	terminal nucleotidyltransferase 5A

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables poly(A) RNA polymerase activity	IDA IDA: 通过直接分析推断	33882302	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	16713569	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TENT5A 蛋白结构

NTP_transf_7

0
100
200
300
400
442 a.a.

蛋白主名

其他名称

terminal nucleotidyltransferase 5A

HBV X-transactivated gene 11 protein

TENT5A 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	TENT5A	Q96IP4	SH2D2A	Homo sapiens	Q9NP31	Y2H Array	25814554
种属内	TENT5A	Q96IP4	SYK	Homo sapiens	P43405	Validated Y2H	25814554
种属内	TENT5A	Q96IP4	SYK	Homo sapiens	P43405	Y2H Array	25814554
种属内	TENT5A	Q96IP4	ATXN1	Homo sapiens	P54253	Y2H Array	16713569

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Osteogenesis Imperfecta, Type Xviii

OI18	Osteogenesis Imperfecta Type 18
Osteogenesis Imperfecta, Type 18	Osteogenesis Imperfecta 18

Osteogenesis Imperfecta, Type Iii

Osteogenesis Imperfecta Type Iii	OI3
Oi, Type Iii	Osteogenesis Imperfecta Type 3
Oi Type Iii	Oi Type 3
Progressive Deforming Osteogenesis Imperfecta	Severe Osteogenesis Imperfecta
Osteogenesis Imperfecta, Progressively Deforming, With Normal Sclerae	Progressively Deforming Osteogenesis Imperfecta With Normal Sclera
Osteogenesis Imperfecta, Progressively Deforming With Normal Sclerae	Progressively Deforming Oi
Osteogenesis Imperfecta 3	Oi-Iii
Progressively Deforming Osteogenesis Imperfecta With Normal Sclerae

Pyloric Stenosis

Esophageal Atresia

Tracheoesophageal Fistula	Congenital Atresia Of Esophagus
Congenital Imperforate Esophagus	Imperforate Esophagus
Oesophageal Atresia	Te Fistula
Tef	Tracheoesophageal Fistula With Or Without Esophageal Atresia

Dentinogenesis Imperfecta

Hereditary Opalescent Dentin	Dentinogenesis Imperfecta Without Osteogenesis Imperfecta
Dgi	Capdepont Teeth
Dgi Without Oi	Di
Non-Syndromic Dgi	Non-Syndromic Dentinogenesis Imperfecta
Opalescent Teeth Without Oi	Opalescent Teeth Without Osteogenesis Imperfecta
Opalescent Dentin

Cole-Carpenter Syndrome

Cole Carpenter Syndrome	Bone Fragility Craniosynostosis Proptosis Hydrocephalus
Bone Fragility With Craniosynostosis, Ocular Proptosis, Hydrocephalus, And Distinctive Facial Features	Bone Fragility-Craniosynostosis-Proptosis-Hydrocephalus Syndrome

Small Cell Carcinoma

Small Cell Carcinoma, Intermediate Cell	Intermediate Cell Small Cell Carcinoma
Small Cell Carcinoma - Intermediate Cell	Small Cell Carcinoma Of Lung
Carcinoma, Small Cell

Scoliosis

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Brittle Bone Disorder

Osteogenesis Imperfecta	Brittle Bone Disease
Fragilitas Ossium	Osteopsathyrosis
Lobstein Disease	Oi
Vrolik Disease	Lobstein'S Disease
Lobstein'S Syndrome	Vrolik'S Disease
Porak And Durante Disease	Glass Bone Disease
Osteogenesis Imperfecta, Dominant Perinatal Lethal	Osteogenesis Imperfecta, Recessive Perinatal Lethal
Brittle Bone Syndrome	Oi - [Osteogenesis Imperfecta]
Ossium Fragility	Osteitis Fragilitans
Bony Fragility	Blue Sclera With Fragility Of Bone And Deafness
White Blue Sclera - Fragility Of Bone - Deafness

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14367	TENT5A Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	TENT5A	RGD	RGD:1311381
Macaca mulatta	TENT5A	VGNC	VGNC:79133
Felis catus	TENT5A	VGNC	VGNC:102534
Bos taurus	TENT5A	VGNC	VGNC:28815
Mus musculus	TENT5A	MGD	MGI:2670964
Canis familiaris	TENT5A	VGNC	VGNC:40681

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TENT5A - terminal nucleotidyltransferase 5A Gene

关于 TENT5A

功能概要

TENT5A 基因产物(1)

TENT5A 蛋白结构

TENT5A 蛋白互作信息

关联疾病

直系同源

热门区域

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TENT5A - terminal nucleotidyltransferase 5A Gene

关于 TENT5A

功能概要

TENT5A 基因产物(1)

TENT5A 蛋白结构

TENT5A 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z