2. Gene
  3. SRSF11 - serine and arginine rich splicing factor 11 Gene

SRSF11 - serine and arginine rich splicing factor 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：富丝氨酸和精氨酸的剪接因子 11

种属: Homo sapiens

同用名: p54; NET2; SFRS11; dJ677H15.2

基因 ID: 9295 | 基因类型: protein coding

关于 SRSF11

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:70,205,696-70,253,052 (from NCBI)

This gene has 18 transcripts (splice variants), 280 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 46.2), skin (RPKM 32.0) and 25 other tissues.

功能概要

该基因编码 54-kD 的核蛋白，其中包含一个富含精氨酸/丝氨酸的区域，类似于前体 mRNA 剪接因子中发现的片段。虽然这种蛋白质的功能尚不清楚，但结构和免疫定位数据表明它可能在 pre-mRNA 加工中发挥作用。可变剪接导致编码不同蛋白质的多个转录变体。此外，在 12 号染色体上发现了该基因的假基因。[RefSeq 提供，2010 年 9 月]

This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010]

SRSF11 基因产物(21)

mRNA Protein Name
NM_001190987.3 NP_001177916.1 serine/arginine-rich splicing factor 11 isoform 2
NM_001350605.2 NP_001337534.1 serine/arginine-rich splicing factor 11 isoform 1
NM_001350606.2 NP_001337535.1 serine/arginine-rich splicing factor 11 isoform 1
NM_001350607.2 NP_001337536.1 serine/arginine-rich splicing factor 11 isoform 2
NM_001350608.2 NP_001337537.1 serine/arginine-rich splicing factor 11 isoform 3
NM_001350609.2 NP_001337538.1 serine/arginine-rich splicing factor 11 isoform 4
NM_001350610.2 NP_001337539.1 serine/arginine-rich splicing factor 11 isoform 5
NM_001350611.2 NP_001337540.1 serine/arginine-rich splicing factor 11 isoform 6
NM_001350612.2 NP_001337541.1 serine/arginine-rich splicing factor 11 isoform 7
NM_001350613.2 NP_001337542.1 serine/arginine-rich splicing factor 11 isoform 7
NM_001350614.2 NP_001337543.1 serine/arginine-rich splicing factor 11 isoform 8
NM_001350615.2 NP_001337544.1 serine/arginine-rich splicing factor 11 isoform 8
NM_001350616.2 NP_001337545.1 serine/arginine-rich splicing factor 11 isoform 8
NM_001394402.1 NP_001381331.1 serine/arginine-rich splicing factor 11 isoform 9
NM_001394403.1 NP_001381332.1 serine/arginine-rich splicing factor 11 isoform 9
NM_001394404.1 NP_001381333.1 serine/arginine-rich splicing factor 11 isoform 3
NM_001394405.1 NP_001381334.1 serine/arginine-rich splicing factor 11 isoform 4
NM_001394406.1 NP_001381335.1 serine/arginine-rich splicing factor 11 isoform 1
NM_001394407.1 NP_001381336.1 serine/arginine-rich splicing factor 11 isoform 2
NM_001394408.1 NP_001381337.1 serine/arginine-rich splicing factor 11 isoform 2
NM_004768.5 NP_004759.1 serine/arginine-rich splicing factor 11 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
20195357 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SRSF11 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (37 - 101)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 484 a.a.
蛋白主名 其他名称

serine/arginine-rich splicing factor 11

SR splicing factor 11

SRSF11 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SRSF11 Q05519 g4xuv3_human Homo sapiens G4XUV3
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 ARL6IP4 Homo sapiens Q66PJ3-3
Validated Y2H
25416956
种属内
SRSF11 Q05519 ARL6IP4 Homo sapiens Q66PJ3-3
Y2H Array
25416956
种属内
SRSF11 Q05519 SREK1 Homo sapiens Q8WXA9
Y2H Array
25416956
种属内
SRSF11 Q05519 SREK1 Homo sapiens Q8WXA9
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 PUF60 Homo sapiens Q9UHX1
Y2H Array
25416956
种属内
SRSF11 Q05519 PUF60 Homo sapiens Q9UHX1
Anti Tag CoIP
33961781
种属内
SRSF11 Q05519 PUF60 Homo sapiens Q9UHX1
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 PUF60 Homo sapiens Q9UHX1
Validated Y2H
25416956
种属内
SRSF11 Q05519 TANK Homo sapiens Q92844
Y2H Array
25416956
种属内
SRSF11 Q05519 TANK Homo sapiens Q92844
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 RBM39 Homo sapiens Q14498
Y2H Array
25416956
种属内
SRSF11 Q05519 ARL6IP4 Homo sapiens Q66PJ3-4
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 GATC Homo sapiens O43716
Validated Y2H
25416956
种属内
SRSF11 Q05519 GATC Homo sapiens O43716
Y2H Array
25416956
种属内
SRSF11 Q05519 GATC Homo sapiens O43716
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 SDCBP Homo sapiens O00560
Validated Y2H
25416956
种属内
SRSF11 Q05519 SDCBP Homo sapiens O00560
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 HYI Homo sapiens Q5T013
Y2H Array
25416956
种属内
SRSF11 Q05519 HYI Homo sapiens Q5T013
Y2H Prey Pooling
25416956
种属内
SRSF11 Q05519 ETS1 Homo sapiens P14921
Y2H Array
21988832
种属内
SRSF11 Q05519 ETS1 Homo sapiens P14921
Display Tech
20195357
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13792 SRSF11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SRSF11 VGNC VGNC:35299
Rattus norvegicus SRSF11 RGD RGD:1559953
Macaca mulatta SRSF11 VGNC VGNC:77818
Felis catus SRSF11 VGNC VGNC:65694
Canis familiaris SRSF11 VGNC VGNC:46817
Mus musculus SRSF11 MGD MGI:1916457
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