2. Anti-infection
  3. HBV
  4. LPRP-Et-97543

LPRP-Et-97543 是一种有效的抗 HBV 活性分子。LPRP-Et-97543 降低 Core、S 和 preS 活性，但不降低 X 启动子活性。LPRP-Et-97543 可用于急性和慢性 HBV 感染研究。

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LPRP-Et-97543 Chemical Structure

LPRP-Et-97543 Chemical Structure

CAS No. : 84638-48-2

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LPRP-Et-97543 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LPRP-Et-97543 is a potent anti-HBV agent. LPRP-Et-97543 reduces Core, S, and preS but not X promoter activities. LPRP-Et-97543 can be used for acute and chronic HBV infections research[1].

体外研究
(In Vitro)

LPRP-Et-97543 (0.625-40 μg/ml; 3 days) causes cytotoxic effects at doses >10 μg/ml in HepG2.2.15 and HBV-transfected Huh7 cells[1].
LPRP-Et-97543 (2.5-10 μg/ml; 3 days) has inhibitory effects on HBsAg and HBeAg secretions. And the HBeAg inhibition rate is higher than the HBsAg inhibition rate in HepG2.2.15 cells[2].
LPRP-Et-97543 (2.5-10 μg/ml; 2 days after transfected with pHBV1.2 plasmid for 2 days) significantly reduces both precore/pregenomic and major S/preS RNA with the LPRP-Et-97543 inhibition potential higher on surface RNA than on the precore/pregenomic RNA[2].
LPRP-Et-97543 (2.5-10 μg/ml; 2 days after transfected with pHBV1.2 plasmid for 2 days) potently reduces intracellular LHBsAg and HBcAg protein levels compared to vehicle controls. Additionally, LPRP-Et-97543 potently inhibits the replication HBV DNAlevel in HBV transfected Huh7 cells[2].
LPRP-Et-97543 (2.5-10 μg/ml; 2 days after transfected with pHBV1.2 plasmid for 2 days) reduces nuclear p65/p50 NF-κB protein expression and reduces phosphorylated NF-κBp65 in Huh7 cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LPRP-Et-97543 相关抗体:

Western Blot Analysis[1]

Cell Line: Huh7 cells with or without pHBV1.2
Concentration: 2.5-10 μg/ml
Incubation Time: 2 days
Result: Decreased nuclear and nuclear p-p65 expression and increased cytoplasmic IκBα expression.
分子量

300.31

Formula

C17H16O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LPRP-Et-97543 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LPRP-Et-9754384638-48-2HBVHepatitis B virusanti-HBVHBV infectionCoreSpreS HBsAgHBeAgInhibitorinhibitorinhibit

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目录号：
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