2. Anti-infection Immunology/Inflammation GPCR/G Protein Neuronal Signaling
  3. Dengue virus Flavivirus Fungal Bacterial Histamine Receptor
  4. Nimbin

Nimbin  (Synonyms: 宁宾)

目录号: HY-N3187 纯度: ≥98.0%
COA 产品使用指南 技术支持

Nimbin 是一种从 Azadirachta 中分离的中间体柠檬苦素，可防止 tau 聚集并增加细胞活力。Nimbin 有效抑制登革病毒 (dengue virus) 的包膜蛋白。Nimbin 具有抗炎，解热，抗真菌，抗组胺，防腐，抗氧化剂，抗癌和抗病毒特性，并可以穿越血脑屏障。

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Nimbin Chemical Structure

Nimbin Chemical Structure

CAS No. : 5945-86-8

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规格 价格 是否有货 数量
1 mg ￥3200
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Nimbin 相关抗体

Top Publications Citing Use of Products

查看 Histamine Receptor 亚型特异性产品:

查看所有亚型
H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier[1][2][3].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 20 μM
Compound: 25
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21381696]
AZ-521 cell line IC50
> 20 μM
Compound: 25
Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21381696]
SK-BR-3 IC50
> 20 μM
Compound: 25
Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21381696]
分子量

540.60

Formula

C30H36O9
CAS 号
性状

固体

颜色

White to off-white

中文名称

宁宾
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

COA (300 KB)

产品使用指南 (1538 KB)
参考文献

Nimbin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nimbin5945-86-8宁宾Dengue virusFlavivirusFungalBacterialHistamine ReceptorDENVTauaggregationintermediatelimonoidAlzheimer'sdiseaseanti-canceranti-viralBBBInhibitorinhibitorinhibit

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