1. Anti-infection Membrane Transporter/Ion Channel
  2. Parasite Potassium Channel
  3. Quinine hemisulfate hydrate

Quinine hemisulfate hydrate  (Synonyms: 硫酸奎宁水合物)

目录号: HY-D0143B
产品使用指南

Quinine hemisulfate hydrate 是一种从金鸡纳树皮中提取的生物碱,具有抗疟疾的作用。Quinine hemisulfate hydrate 是一种钾离子通道 (potassium channel) 抑制剂,可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其 IC50 值为 169 μM。

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Quinine hemisulfate hydrate Chemical Structure

Quinine hemisulfate hydrate Chemical Structure

CAS No. : 207671-44-1

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1 g ¥100
1 - 2 周
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Other Forms of Quinine hemisulfate hydrate:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM[1][2].

IC50 & Target

IC50: Parasite[1], 169 μM (mSlo3)[2]

Clinical Trial
分子量

391.48

Formula

C20H24N2O2.1/2H2O4S.H2O

CAS 号
中文名称

硫酸奎宁水合物

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Quinine hemisulfate hydrate
目录号:
HY-D0143B
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