2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 疾病相关化合物库
  6. 抗寄生虫化合物库
抗寄生虫化合物库 - Antiparasitic Compound library

Cat. No.: HY-L082

寄生虫是生活在宿主身上或宿主体内的病原体，从宿主体内获取食物或以宿主为代价获取食物。人类的寄生虫包括原生动物、蠕虫和外寄生虫(生活在宿主外表面的有机体)等。寄生虫感染会导致很多疾病发生，最常见的寄生虫感染是通过摄入受污染的食物、水或通过节肢动物（如蚊虫等）叮咬传播给宿主，这些节肢动物可作为中间宿主和媒介。寄生虫病的危害仍是普遍存在的公共卫生问题，特别是在发展中国家。每年有上亿人感染致病寄生虫，特别是在世界热带和亚热带地区，估计造成 100 万人死亡。因此，迫切需要新型抗寄生药物的开发。

MCE 可以提供 489 种具有明确抗寄生虫作用的小分子化合物，可以用于新适应症的开发及新型抗寄生虫靶点的鉴定。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗寄生虫化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，477 个产品以 10 mM 浓度提供，12 个产品以 2 mM 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 489 bioactive compounds with validated anti-parasitic activity that can be used for high throughput screening (HTS) and high content screening (HCS).

•   Compounds in this library have a variety of antiparasitic activities, including anti-Plasmodium, anti-Leishmania, anti-Filariasis, anti-Lymphatic Filariasis, etc.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 489 antiparasitic compounds supplied as pre-dissolved Solutions or Solid.
Solution: 477 compounds supplied in 10 mM solution, 12 compounds supplied in 2 mM solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

HIV (12)

Akt (8)

PARP (7)

STAT (6)

COX (5)

MMP (5)

PI4K (5)

HSV (4)

AMPK (3)

mTOR (3)

PI3K (3)

Wnt (3)

BCRP (2)

CaMK (2)

CDK (2)

HCV (2)

JNK (2)

PKA (2)

PKC (2)

AP-1 (1)

CCR (1)

CMV (1)

CXCR (1)

EGFR (1)

ERK (1)

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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Antiparasitic Compound library
    目录号：
    HY-L082
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