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  3. (±)-Epicatechin-13C3

(±)-Epicatechin-13C3  (Synonyms: 表儿茶素-13C3)

目录号: HY-N0001S
产品使用指南

(±)-Epicatechin-13C313C 标记的 (±)-Epicatechin。 (-)-Epicatechin 抑制环加氧酶-1 (COX-1) , IC50为 3.2 μM。(-)-Epicatechin 通过阻断 NF-κB 的 p65 亚基的核定位来抑制 IL-1β 诱导的 iNOS 表达。

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(±)-Epicatechin-<sup>13</sup>C<sub>3</sub> Chemical Structure

(±)-Epicatechin-13C3 Chemical Structure

CAS No. : 1217780-28-3

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Other Forms of (±)-Epicatechin-13C3:

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  • 生物活性

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  • 参考文献

生物活性

(±)-Epicatechin-13C3 is the 13C labeled (±)-Epicatechin. (-)-Epicatechin (HY-N0001) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

293.25

Formula

C1213C3H14O6

CAS 号
非标记 CAS

490-46-0

中文名称

表儿茶素-13C3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(±)-Epicatechin-13C3
目录号:
HY-N0001S
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