1. GPCR/G Protein Neuronal Signaling
  2. mGluR
  3. (RS)-4CPG

(RS)-4CPG  (Synonyms: (RS)-4-Carboxyphenylglycine)

目录号: HY-100617A
产品使用指南

(RS)-4CPG ((RS)-4-Carboxyphenylglycine) 是一种I型代谢型谷氨酸受体拮抗剂,具有阻断LTP诱导的活性。在缺乏IP3R1的小鼠中,(RS)-4CPG(500μM)可几乎阻断I型代谢型谷氨酸受体激活引起的长时程增强(LTP),在IP3R1(-/-)小鼠中LTP为117.6±1.7%(n = 8),在IP3R1(+/+)小鼠中为116.9±1.8%(n = 5)。

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(RS)-4CPG Chemical Structure

(RS)-4CPG Chemical Structure

CAS No. : 7292-81-1

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Other Forms of (RS)-4CPG:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(RS)-4CPG ((RS)-4-Carboxyphenylglycine) is a type I metabotropic glutamate receptor antagonist with activity in blocking LTP induction. In mice lacking IP3R1, (RS)-4CPG (500μM) nearly blocked long-term potentiation (LTP) induced by type I metabotropic glutamate receptor activation, with LTP of 117.6±1.7% (n = 8) in IP3R1(-/-) mice and 116.9±1.8% (n = 5) in IP3R1(+/+) mice.

分子量

195.17

Formula

C9H9NO4

CAS 号
中文名称

(RS)-4-羧苯基甘氨酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(RS)-4CPG
目录号:
HY-100617A
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