2. GPCR/G Protein
  3. Endothelin Receptor
  4. TAK 044

TAK 044 是内皮素受体的拮抗剂。TAK 044在多种动物模型中强烈抑制了 ET 诱导的退化。TAK 044 可用于急性心肌梗死、急性肾功能衰竭、急性肝功能障碍、蛛网膜下腔出血等 ET 相关疾病的研究。

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Custom Peptide Synthesis

TAK 044

TAK 044 Chemical Structure

CAS No. : 157380-72-8

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

TAK 044 相关抗体

Top Publications Citing Use of Products

查看 Endothelin Receptor 亚型特异性产品:

查看所有亚型
ETA ETB

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage[1].

分子量

971.98

Formula

C45H51N9Na2O11S
CAS 号
Sequence

cyclo({d-Asp}-{α-amino-γ-oxo-4-phenyl-1-piperazinebutanoyl-Asp}-Asp-{d-(2-thienyl)glycine}-Leu-{d-Trp}) (disodium salt)
Sequence Shortening

cyclo({d-Asp}-{α-amino-γ-oxo-4-phenyl-1-piperazinebutanoyl-Asp}-D-{d-(2-thienyl)glycine}-L-{d-Trp}) (disodium salt)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TAK 044 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAK 044157380-72-8TAK044TAK-044Endothelin ReceptorAcute renal failureCoronary arteryAK 044Endothelin Receptor AntagonistHepatic dysfunctionMyocardial infarctionSubarachnoid hemorrhageVascular proliferationInhibitorinhibitorinhibit

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产品名称：
TAK 044
目录号：
HY-105168
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