2. Others Immunology/Inflammation
  3. Isotope-Labeled Compounds COX
  4. Tolfenamic acid-13C6

Tolfenamic acid-13C6  (Synonyms: 托芬那酸-13C6; GEA 6414-13C6)

目录号: HY-B0335S1
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摩尔计算器

Tolfenamic acid-13C6 是 13C6 标记的 Tolfenamic acid。Tolfenamic Acid (GEA 6414) 是一种非甾体抗炎剂和抗癌剂，能够选择性地抑制 COX-2 的活性，在 LPS 诱导的犬 DH82 单核细胞/巨噬细胞中，对 COX-2 的 IC50 值为 13.49 μM (3.53 μg/mL)，对 COX-1 无作用。

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Tolfenamic acid-<sup>13</sup>C<sub>6</sub> Chemical Structure

Tolfenamic acid-13C6 Chemical Structure

CAS No. : 1420043-61-3

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Other Forms of Tolfenamic acid-13C6:

Tolfenamic acid-13C6 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

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COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tolfenamic acid-13C6 is the 13C6 labeled Tolfenamic acid. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tolfenamic acid-13C6 相关抗体:
分子量

267.66

Formula

C813C6H12ClNO2
CAS 号
非标记 CAS

13710-19-5
中文名称

托芬那酸-13C6；托灭酸-13C6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tolfenamic acid-13C6 相关分类

  • 摩尔计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Tolfenamic acid-13C61420043-61-3GEA 6414-13C6托芬那酸-13C6托灭酸-13C6Isotope-Labeled CompoundsCOXCyclooxygenaseInhibitorinhibitorinhibit

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