2. Epigenetics
  3. Histone Methyltransferase
  4. WDR5-MYC-IN-1

WDR5-MYC-IN-1 (compound 4o) 是一种有效的 WDR5-MYC 相互作用抑制剂，其 Ki 值为 1.0 µM。WDR5-MYC-IN-1 表现出抗增殖活性。

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WDR5-MYC-IN-1 Chemical Structure

WDR5-MYC-IN-1 Chemical Structure

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WDR5-MYC-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Histone Methyltransferase 亚型特异性产品:

查看所有亚型
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

WDR5-MYC-IN-1 (compound 4o) is a potent WDR5-MYC interaction inhibitor with a Ki value of 1.0 µM. WDR5-MYC-IN-1 shows antiproliferative activity[1].

IC50 & Target

Ki: 1.0 µM (WDR5-MYC)[1]
体外研究
(In Vitro)

WDR5-MYC-IN-1 (compound 4o) 显示出抗增殖活性，对 RAJI、RAMOS、SUDHL4、HL-60、H1299 细胞的 IC50 值分别为 1.52、1.51、2.20、5.32、7.40 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

WDR5-MYC-IN-1 相关抗体:

Cell Proliferation Assay[1]

Cell Line: RAJI, RAMOS, SUDHL4, HL-60, H1299 cells
Concentration:
Incubation Time:
Result: Showed antiproliferative activity with IC50s of 1.52, 1.51, 2.20, 5.32, 7.40 µM for RAJI, RAMOS, SUDHL4, HL-60, H1299 cells, respectively.
分子量

290.36

Formula

C12H10N4OS2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

WDR5-MYC-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WDR5-MYC-IN-1Histone MethyltransferaseantiproliferativecancerInhibitorinhibitorinhibit

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产品名称：
WDR5-MYC-IN-1
目录号：
HY-163774
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