2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. Drug-Linker Conjugates for ADC Topoisomerase
  4. DBCO-PEG3-VC-Exatecan

DBCO-PEG3-VC-Exatecan (compound 25) 是一种 ADC 药物-连接子偶联物 (Drug-Linker Conjugate for ADC)，由 ADC linker (DBCO-PEG3-VC) 和 DNA 拓扑异构酶 I (topoisomerase I) 抑制剂 Exatecan (HY-13631) 偶联而成。

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DBCO-PEG3-VC-Exatecan Chemical Structure

DBCO-PEG3-VC-Exatecan Chemical Structure

CAS No. : 2754384-70-6

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规格 价格 是否有货
1 mg ￥2900
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5 mg 现货 询问价格 & 货期
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DBCO-PEG3-VC-Exatecan 相关抗体

Top Publications Citing Use of Products

查看 Drug-Linker Conjugates for ADC 亚型特异性产品:

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631)[1].

IC50 & Target[1]

Camptothecins

 

分子量

1331.44

Formula

C71H79FN10O15
CAS 号
性状

固体

颜色

Off-white to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

DBCO-PEG3-VC-Exatecan 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DBCO-PEG3-VC-Exatecan2754384-70-6Drug-Linker Conjugates for ADCTopoisomeraseDrug-Linker Conjugate for ADCDBCO-PEG3-VCtopoisomerase IExatecanInhibitorinhibitorinhibit

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目录号：
HY-164792
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