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  2. JMJD7 - jumonji domain containing 7 Gene

JMJD7 - jumonji domain containing 7 Gene

中文名称:含 Jumonji 域 7

种属: Homo sapiens

基因 ID: 100137047 | 基因类型: protein coding

关于 JMJD7

This gene has 6 transcripts (splice variants), 171 orthologues and 4 paralogues. Ubiquitous expression in skin (RPKM 20.1), esophagus (RPKM 12.8) and 25 other tissues.

功能概要

该基因编码一种具有 JmjC 结构域的高度保守的蛋白质,该结构域是 cupin 金属酶超家族的一部分。 JmjC 蛋白可能作为 2-酮戊二酸-Fe (II) 依赖性双加氧酶发挥作用。大多数组织还表达从该基因到下游磷脂酶 A2、IVB 组 (细胞溶质) 基因的通读转录本,其中一些可能编码融合蛋白,该融合蛋白结合了该蛋白的 N 端与磷脂酶 A2、IVB 组蛋白。[RefSeq 提供,2008 年 7 月]

This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream Phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the Phospholipase A2, group IVB protein. [provided by RefSeq, Jul 2008]

JMJD7 基因产物(1)

mRNA Protein Name
NM_001114632.2 NP_001108104.1 bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aminopeptidase activity IDA
IDA: 通过直接分析推断
28847961 GOA
enables endopeptidase activity IDA
IDA: 通过直接分析推断
28847961 GOA
enables methylated histone binding IDA
IDA: 通过直接分析推断
28847961 GOA
enables monooxygenase activity IDA
IDA: 通过直接分析推断
29915238 GOA
enables peptidyl-lysine 3-dioxygenase activity EXP
EXP: 通过实验结果推断
29915238 GOA
enables peptidyl-lysine 3-dioxygenase activity IDA
IDA: 通过直接分析推断
29915238 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein hydroxylation IDA
IDA: 通过直接分析推断
29915238 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
29915238 GOA
located in nucleus IDA
IDA: 通过直接分析推断
29915238 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

JMJD7 蛋白结构

Cupin_8

Cupin_8: Cupin-like domain (40 - 297)

  • 0
  • 100
  • 200
  • 316 a.a.
蛋白主名 其他名称

bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7

L-lysine (3S)-hydroxylase JMJD7

JMJD7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
JMJD7 P0C870 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
种属内
JMJD7 P0C870 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
种属内
JMJD7 P0C870 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
种属内
JMJD7 P0C870 POM121 Homo sapiens Q96HA1-2
Validated Y2H
32296183
种属内
JMJD7 P0C870 FOXI1 Homo sapiens Q12951-2
Validated Y2H
32296183
种属内
JMJD7 P0C870 OXER1 Homo sapiens Q8TDS5
Y2H Array
32296183
种属内
JMJD7 P0C870 OXER1 Homo sapiens Q8TDS5
Y2H Prey Pooling
32296183
种属内
JMJD7 P0C870 OXER1 Homo sapiens Q8TDS5
Validated Y2H
32296183
种属内
JMJD7 P0C870 SAMD11 Homo sapiens Q96NU1
Validated Y2H
32296183
种属内
JMJD7 P0C870 VAC14 Homo sapiens Q08AM6
Y2H Array
25416956
种属内
JMJD7 P0C870 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
25416956
种属内
JMJD7 P0C870 LAMP2 Homo sapiens P13473-2
Validated Y2H
32814053
种属内
JMJD7 P0C870 LAMP2 Homo sapiens P13473-2
Y2H Array
32814053
种属内
JMJD7 P0C870 LAMP2 Homo sapiens P13473-2
Y2H Pooling
32814053
种属内
JMJD7 P0C870 UBAP2 Homo sapiens Q5T6F2
Y2H Array
32296183
种属内
JMJD7 P0C870 UBAP2 Homo sapiens Q5T6F2
Y2H Prey Pooling
32296183
种属内
JMJD7 P0C870 UBAP2 Homo sapiens Q5T6F2
Validated Y2H
32296183
种属内
JMJD7 P0C870 SH3GLB1 Homo sapiens Q9Y371
Validated Y2H
32814053
种属内
JMJD7 P0C870 SH3GLB1 Homo sapiens Q9Y371
Y2H Array
32814053
种属内
JMJD7 P0C870 SH3GLB1 Homo sapiens Q9Y371
Y2H Pooling
32814053
种属内
JMJD7 P0C870 RAN Homo sapiens P62826
Y2H Array
32814053
种属内
JMJD7 P0C870 RAN Homo sapiens P62826
Y2H Pooling
32814053
种属内
JMJD7 P0C870 RAN Homo sapiens P62826
Validated Y2H
32814053
种属内
JMJD7 P0C870 HSPB1 Homo sapiens P04792
Validated Y2H
32814053
种属内
JMJD7 P0C870 HSPB1 Homo sapiens P04792
Y2H Array
32814053
种属内
JMJD7 P0C870 HSPB1 Homo sapiens P04792
Y2H Pooling
32814053
种属内
JMJD7 P0C870 PRPF40A Homo sapiens O75400-2
Validated Y2H
32814053
种属内
JMJD7 P0C870 PRPF40A Homo sapiens O75400-2
Y2H Array
32814053
种属内
JMJD7 P0C870 PRPF40A Homo sapiens O75400-2
Y2H Pooling
32814053
种属内
JMJD7 P0C870 CASP6 Homo sapiens P55212
Validated Y2H
32814053
种属内
JMJD7 P0C870 CASP6 Homo sapiens P55212
Y2H Array
32814053
种属内
JMJD7 P0C870 CASP6 Homo sapiens P55212
Y2H Pooling
32814053
种属内
JMJD7 P0C870 WFS1 Homo sapiens O76024
Validated Y2H
32814053
种属内
JMJD7 P0C870 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
种属内
JMJD7 P0C870 WFS1 Homo sapiens O76024
Y2H Array
32814053
种属内
JMJD7 P0C870 DRG2 Homo sapiens P55039
Validated Y2H
32296183
种属内
JMJD7 P0C870 DRG2 Homo sapiens P55039
Y2H Prey Pooling
32296183
种属内
JMJD7 P0C870 DRG2 Homo sapiens P55039
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Bos taurus JMJD7 VGNC VGNC:55118
Rattus norvegicus JMJD7 RGD RGD:2290039
Mus musculus JMJD7 MGD MGI:3845785
Canis familiaris JMJD7 VGNC VGNC:59115