2. Gene
  3. SAMD11 - sterile alpha motif domain containing 11 Gene

SAMD11 - sterile alpha motif domain containing 11 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含无菌 alpha 基序结构域 11

种属: Homo sapiens

同用名: MRS

基因 ID: 148398 | 基因类型: protein coding

关于 SAMD11

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:923,923-944,574 (from NCBI)

This gene has 15 transcripts (splice variants), 199 orthologues, 18 paralogues and is associated with 1 phenotype. Ubiquitous expression in prostate (RPKM 7.4), endometrium (RPKM 5.9) and 25 other tissues.

功能概要

预计将启用多种功能，包括组蛋白结合活性；蛋白质结构域特异性结合活性；和蛋白质自缔合。预测参与转录的负调控，DNA 模板化。预计在 RNA 聚合酶 II 的转录负调节上游或负调节内起作用。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including histone binding activity; protein domain specific binding activity; and protein self-association. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SAMD11 基因产物(3)

mRNA Protein Name
NM_001385640.1 NP_001372569.1 sterile alpha motif domain-containing protein 11 isoform 2
NM_001385641.1 NP_001372570.1 sterile alpha motif domain-containing protein 11 isoform 1
NM_152486.4 NP_689699.3 sterile alpha motif domain-containing protein 11 isoform 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SAMD11 蛋白结构

SAM_2

SAM_2: SAM domain (Sterile alpha motif) (543 - 597)

  • 0
  • 200
  • 400
  • 600
  • 681 a.a.
蛋白主名 其他名称

sterile alpha motif domain-containing protein 11

SAM domain-containing protein 11

SAMD11 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SAMD11 Q96NU1 RTL8C Homo sapiens A6ZKI3
Y2H Array
32296183
Intra SAMD11 Q96NU1 RTL8C Homo sapiens A6ZKI3
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
32296183
Intra SAMD11 Q96NU1 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 NFKBID Homo sapiens Q8NI38
Y2H Array
32296183
Intra SAMD11 Q96NU1 NFKBID Homo sapiens Q8NI38
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra SAMD11 Q96NU1 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra SAMD11 Q96NU1 KRTAP5-7 Homo sapiens Q6L8G8
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 KRTAP5-7 Homo sapiens Q6L8G8
Y2H Array
32296183
Intra SAMD11 Q96NU1 ZMYND12 Homo sapiens Q9H0C1
Y2H Array
32296183
Intra SAMD11 Q96NU1 ZMYND12 Homo sapiens Q9H0C1
Validated Y2H
32296183
Intra SAMD11 Q96NU1 ZMYND12 Homo sapiens Q9H0C1
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 PRR20D Homo sapiens P86480
Y2H Array
32296183
Intra SAMD11 Q96NU1 PRR20D Homo sapiens P86480
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 TSC1 Homo sapiens Q86WV8
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 TSC1 Homo sapiens Q86WV8
Y2H Array
32296183
Intra SAMD11 Q96NU1 PLAGL2 Homo sapiens Q9UPG8
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 PLAGL2 Homo sapiens Q9UPG8
Validated Y2H
32296183
Intra SAMD11 Q96NU1 PLAGL2 Homo sapiens Q9UPG8
Y2H Array
32296183
Intra SAMD11 Q96NU1 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra SAMD11 Q96NU1 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 TRAF1 Homo sapiens Q13077
Y2H Array
32296183
Intra SAMD11 Q96NU1 TRIB3 Homo sapiens Q96RU7
Validated Y2H
32296183
Intra SAMD11 Q96NU1 TRIB3 Homo sapiens Q96RU7
Y2H Array
32296183
Intra SAMD11 Q96NU1 TRIB3 Homo sapiens Q96RU7
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 CT55 Homo sapiens Q8WUE5
Y2H Array
32296183
Intra SAMD11 Q96NU1 CT55 Homo sapiens Q8WUE5
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
32296183
Intra SAMD11 Q96NU1 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
Intra SAMD11 Q96NU1 JMJD7 Homo sapiens P0C870
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 JMJD7 Homo sapiens P0C870
Y2H Array
32296183
Intra SAMD11 Q96NU1 ECM1 Homo sapiens Q16610
Y2H Array
32296183
Intra SAMD11 Q96NU1 ECM1 Homo sapiens Q16610
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra SAMD11 Q96NU1 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 BPIFA1 Homo sapiens Q9NP55
Y2H Prey Pooling
32296183
Intra SAMD11 Q96NU1 BPIFA1 Homo sapiens Q9NP55
Y2H Array
32296183
Intra SAMD11 Q96NU1 BPIFA1 Homo sapiens Q9NP55
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Chronic Intestinal Vascular Insufficiency

Chronic Mesenteric Ischemia

Cmi - Chronic Mesenteric Ischaemia
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12423 SAMD11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SAMD11 VGNC VGNC:45849
Bos taurus SAMD11 VGNC VGNC:59361
Felis catus SAMD11 VGNC VGNC:64861
Rattus norvegicus SAMD11 RGD RGD:1310271
Mus musculus SAMD11 MGD MGI:2446220
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