2. Gene
  3. Baiap2 - brain-specific angiogenesis inhibitor 1-associated protein 2 Gene

Baiap2 - brain-specific angiogenesis inhibitor 1-associated protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IRSp53

基因 ID: 108100 | 基因类型: protein coding

关于 Baiap2

功能概要

Predicted to enable several functions, including PDZ domain binding activity; identical protein binding activity; and scaffold protein binding activity. Involved in several processes, including actin filament organization; modification of synaptic structure, modulating synaptic transmission; and regulation of cell shape. Acts upstream of or within dendrite development and regulation of synaptic plasticity. Located in Schaffer collateral - CA1 synapse and neuron projection. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Baiap2 基因产物(3)

mRNA Protein Name
NM_001037754.3 NP_001032843.1 brain-specific angiogenesis inhibitor 1-associated protein 2 isoform c
NM_001037755.3 NP_001032844.2 brain-specific angiogenesis inhibitor 1-associated protein 2 isoform a
NM_130862.4 NP_570932.2 brain-specific angiogenesis inhibitor 1-associated protein 2 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10814512 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin crosslink formation IMP
IMP: 通过突变表型推断
17115031 MGI
acts upstream of or within actin filament bundle assembly IGI
IGI: 通过遗传相互作用推断
19208628 MGI
involved in actin filament bundle assembly IMP
IMP: 通过突变表型推断
17115031 MGI
acts upstream of or within dendrite development IMP
IMP: 通过突变表型推断
19208628 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
19193906 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
19193906 MGI
involved in regulation of cell shape IMP
IMP: 通过突变表型推断
17115031 MGI
acts upstream of or within regulation of synaptic plasticity IMP
IMP: 通过突变表型推断
19208628 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
19193906 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
19193906 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
21795692 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

brain-specific angiogenesis inhibitor 1-associated protein 2

BAI-associated protein 2

BAI1-associated protein 2

insulin receptor substrate p53

insulin receptor substrate protein of 53 kDa

insulin receptor tyrosine kinase 53 kDa substrate

Baiap2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Baiap2 Q8BKX1 Diaph1 Mus musculus O08808
Far-WB
10814512
Intra Baiap2 Q8BKX1 Diaph1 Mus musculus O08808
Y2H
10814512
Intra Baiap2 Q8BKX1 Dlg4 Mus musculus Q62108
Anti Bait CoIP
19455133
Intra Baiap2 Q8BKX1 Iqsec2 Mus musculus A4GZ26
Pull Down
19083995
Intra Baiap2 Q8BKX1 Iqsec2 Mus musculus A4GZ26
Y2H
19083995
Intra Baiap2 Q8BKX1 Iqsec2 Mus musculus A4GZ26
Anti Bait CoIP
19083995
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01353 BAIAP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01354 BAIAP2L1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01355 BAIAP2L2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Baiap2 NCBI NCBI:10458
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