2. Gene
  3. Prdm1 - PR domain containing 1, with ZNF domain Gene

Prdm1 - PR domain containing 1, with ZNF domain Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Blimp1; Blimp-1; PRDI-BF1; ZNFPR1A1; b2b1765Clo

基因 ID: 12142 | 基因类型: protein coding

关于 Prdm1

功能概要

Enables histone deacetylase binding activity; promoter-specific chromatin binding activity; and sequence-specific DNA binding activity. Involved in regulation of NK T cell differentiation; regulation of extrathymic T cell differentiation; and regulation of natural killer cell differentiation. Acts upstream of or within several processes, including animal organ development; artery development; and regulation of B cell activation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; reproductive system; retina; and skin. Used to study systemic lupus erythematosus. Orthologous to human PRDM1 (PR/SET domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Prdm1 基因产物(9)

mRNA Protein Name
NM_001405929.1 NP_001392858.1 PR domain zinc finger protein 1 isoform 1
NM_001405930.1 NP_001392859.1 PR domain zinc finger protein 1 isoform 2
NM_001405931.1 NP_001392860.1 PR domain zinc finger protein 1 isoform 3
NM_001405932.1 NP_001392861.1 PR domain zinc finger protein 1 isoform 5
NM_001405933.1 NP_001392862.1 PR domain zinc finger protein 1 isoform 5
NM_001405934.1 NP_001392863.1 PR domain zinc finger protein 1 isoform 6
NM_001405935.1 NP_001392864.1 PR domain zinc finger protein 1 isoform 7
NM_001405936.1 NP_001392865.1 PR domain zinc finger protein 1 isoform 8
NM_007548.5 NP_031574.2 PR domain zinc finger protein 1 isoform 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone methyltransferase binding IPI
IPI: 通过物理相互作用推断
16699504 MGI
enables promoter-specific chromatin binding IDA
IDA: 通过直接分析推断
27102484 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21722636 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
32741026 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within artery morphogenesis IGI
IGI: 通过遗传相互作用推断
24821700 MGI
acts upstream of or within artery morphogenesis IMP
IMP: 通过突变表型推断
24821700 MGI
acts upstream of or within cardiac septum development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within cell fate commitment IMP
IMP: 通过突变表型推断
15750184 MGI
acts upstream of or within coronary vasculature development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within embryonic placenta development IMP
IMP: 通过突变表型推断
15750184 MGI
acts upstream of or within eye photoreceptor cell development IMP
IMP: 通过突变表型推断
20463215 MGI
involved in gene expression IDA
IDA: 通过直接分析推断
16699504 MGI
acts upstream of or within germ cell development IGI
IGI: 通过遗传相互作用推断
19578360 MGI
acts upstream of or within heart valve development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
15750184 MGI
acts upstream of or within intestinal epithelial cell development IMP
IMP: 通过突变表型推断
21670299 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
27002738 MGI
acts upstream of or within maternal placenta development IMP
IMP: 通过突变表型推断
15750184 MGI
acts upstream of or within morphogenesis of a branching structure IMP
IMP: 通过突变表型推断
24821700 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: 通过突变表型推断
21670299 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20463215 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
32741026 MGI
involved in peptidyl-arginine methylation IDA
IDA: 通过直接分析推断
16699504 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
18622394 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
21670299 MGI
involved in regulation of NK T cell differentiation IMP
IMP: 通过突变表型推断
27102484 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: 通过突变表型推断
24821700 MGI
involved in regulation of extrathymic T cell differentiation IMP
IMP: 通过突变表型推断
27102484 MGI
involved in regulation of natural killer cell differentiation IMP
IMP: 通过突变表型推断
27102484 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
28199486 MGI
acts upstream of or within retinal bipolar neuron differentiation IMP
IMP: 通过突变表型推断
28199486 MGI
acts upstream of or within sebum secreting cell proliferation IDA
IDA: 通过直接分析推断
16901790 MGI
acts upstream of or within trophoblast giant cell differentiation IMP
IMP: 通过突变表型推断
22987638 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
25807483 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytoplasm IDA
IDA: 通过直接分析推断
16699504 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
32741026 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
16699504 MGI
located in nucleus IDA
IDA: 通过直接分析推断
16901790 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

PR domain zinc finger protein 1

B lymphocyte induced maturation protein

B lymphocyte-induced maturation protein 1

PR domain-containing protein 1

beta-interferon gene positive regulatory domain I-binding factor

Prdm1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Cross Prdm1 Q60636 SUMO1 Homo sapiens P63165
Anti Tag CoIP
21722636
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11059 PRDM1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prdm1 NCBI NCBI:639
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