Kat2a - K(lysine) acetyltransferase 2A Gene

中文名称：K (赖氨酸) 乙酰转移酶2A

种属: Mus musculus

同用名: Gcn5; Gcn5l2; mmGCN5; 1110051E14Rik

关于 Kat2a

功能概要

该基因编码的蛋白可启动 H3 组蛋白乙酰转移酶活性；染色质结合活性；和组蛋白乙酰转移酶活性（H4-K12 特异性）。涉及多个过程，包括长期记忆；大分子代谢过程的正向调控；和调节调节性 T 细胞分化。作用于多个过程的上游或内部，包括大脑发育；脊索动物胚胎发育；和组蛋白乙酰化。位于有丝分裂纺锤体和细胞核中。 ATAC 复合体和 SAGA 复合体的一部分。以多种结构表达，包括消化系统；中枢神经系统;早孕;泌尿生殖系统；和淋巴系统腺体。与人 KAT2A（赖氨酸乙酰转移酶 2A）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables H3 Histone Acetyltransferase activity; chromatin binding activity; and Histone Acetyltransferase activity (H4-K12 specific). Involved in several processes, including long-term memory; positive regulation of macromolecule metabolic process; and regulation of regulatory T cell differentiation. Acts upstream of or within several processes, including brain development; chordate embryonic development; and histone acetylation. Located in mitotic spindle and nucleus. Part of ATAC complex and SAGA complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system gland. Orthologous to human KAT2A (lysine acetyltransferase 2A). [provided by Alliance of Genome Resources, Apr 2022]