Lta - lymphotoxin A Gene

中文名称：淋巴毒素 A

种属: Mus musculus

同用名: LT; Ltx; Tnfb; LT[a]; LT-[a]; TNFSF1; Tnlg1e; hlb382; LTalpha; Tnfsf1b; LT-alpha; TNF-beta

关于 Lta

功能概要

预测该基因编码的蛋白编码的蛋白可启动肿瘤坏死因子受体结合活性。作用于多个过程的上游或内部，包括淋巴结发育；免疫反应的正向调节；和干扰素-γ 产生的正向调节。预计位于细胞外空间。以多种结构表达，包括胚外成分；直觉;淋巴系统；肝;和生殖系统。该基因的人类直系同源物与多种疾病有关，包括动脉疾病（多种）；自身免疫性疾病（多种）；糖代谢疾病（多种）；利什曼病（多发）；和肺部疾病（多种）。与人类 LTA（淋巴毒素 α）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable tumor necrosis factor receptor binding activity. Acts upstream of or within several processes, including lymph node development; positive regulation of immune response; and positive regulation of interferon-gamma production. Predicted to be located in extracellular space. Is expressed in several structures, including extraembryonic component; gut; hemolymphoid system; liver; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); glucose metabolism disease (multiple); leishmaniasis (multiple); and lung disease (multiple). Orthologous to human LTA (lymphotoxin alpha). [provided by Alliance of Genome Resources, Apr 2022]