Myod1 - myogenic differentiation 1 Gene

种属: Mus musculus

同用名: MYF3; MyoD; Myod-1; bHLHc1

基因 ID: 17927 | 基因类型: protein coding

关于 Myod1

功能概要

Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Contributes to DNA binding activity. Involved in several processes, including cellular response to estradiol stimulus; histone acetylation; and positive regulation of snRNA transcription by RNA polymerase II. Acts upstream of or within several processes, including myotube differentiation; regulation of RNA metabolic process; and skeletal muscle fiber adaptation. Located in euchromatin; myofibril; and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; embryo mesenchyme; limb; limb bud; and musculature. Orthologous to human MYOD1 (myogenic differentiation 1). [provided by Alliance of Genome Resources, Apr 2022]

Myod1 基因产物(1)

mRNA	Protein	Name
NM_010866.2	NP_034996.2	myoblast determination protein 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
contributes to DNA binding	IDA IDA: 通过直接分析推断	2503252	MGI
enables DNA-binding transcription activator activity	IDA IDA: 通过直接分析推断	15706034	MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: 通过直接分析推断	10652346	MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IMP IMP: 通过突变表型推断	15890200	MGI
enables DNA-binding transcription factor activity	IDA IDA: 通过直接分析推断	12037670	MGI
enables DNA-binding transcription factor activity	IMP IMP: 通过突变表型推断	26658965	MGI
enables E-box binding	IDA IDA: 通过直接分析推断	10652346	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: 通过直接分析推断	11714687	MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding	IPI IPI: 通过物理相互作用推断	10652346	MGI
enables bHLH transcription factor binding	IPI IPI: 通过物理相互作用推断	2503252	MGI
enables chromatin DNA binding	IDA IDA: 通过直接分析推断	25085416	MGI
enables chromatin binding	IDA IDA: 通过直接分析推断	16245309	MGI
enables cis-regulatory region sequence-specific DNA binding	IDA IDA: 通过直接分析推断	12486129	MGI
enables enzyme binding	IPI IPI: 通过物理相互作用推断	20833138	MGI
enables promoter-specific chromatin binding	IDA IDA: 通过直接分析推断	25217815	MGI
enables protein binding	IPI IPI: 通过物理相互作用推断	7973707	MGI
enables protein homodimerization activity	IPI IPI: 通过物理相互作用推断	10652346	MGI
enables sequence-specific DNA binding	IDA IDA: 通过直接分析推断	22638570	MGI
enables transcription factor binding	IPI IPI: 通过物理相互作用推断	22638570	MGI
enables ubiquitin protein ligase binding	IPI IPI: 通过物理相互作用推断	19319192	MGI

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in cellular response to estradiol stimulus	IDA IDA: 通过直接分析推断	15706034	MGI
acts upstream of or within cellular response to glucocorticoid stimulus	IDA IDA: 通过直接分析推断	19319192	MGI
acts upstream of or within cellular response to oxygen levels	IDA IDA: 通过直接分析推断	19319192	MGI
acts upstream of or within cellular response to starvation	IDA IDA: 通过直接分析推断	19319192	MGI
acts upstream of or within cellular response to tumor necrosis factor	IDA IDA: 通过直接分析推断	24349514	MGI
involved in muscle cell differentiation	IDA IDA: 通过直接分析推断	15706034	MGI
acts upstream of or within muscle organ development	IDA IDA: 通过直接分析推断	15192231	MGI
acts upstream of or within muscle organ development	IGI IGI: 通过遗传相互作用推断	15634692	MGI
acts upstream of or within myoblast differentiation	IDA IDA: 通过直接分析推断	12037571	MGI
acts upstream of or within myoblast fate determination	IDA IDA: 通过直接分析推断	12486129	MGI
acts upstream of or within myoblast fusion	IMP IMP: 通过突变表型推断	15890200	MGI
acts upstream of or within myotube differentiation	IDA IDA: 通过直接分析推断	9234731	MGI
acts upstream of or within myotube differentiation involved in skeletal muscle regeneration	IMP IMP: 通过突变表型推断	1348494	MGI
involved in negative regulation of chromatin binding	IDA IDA: 通过直接分析推断	26658965	MGI
involved in negative regulation of chromatin binding	IMP IMP: 通过突变表型推断	26658965	MGI
acts upstream of or within negative regulation of myoblast proliferation	IMP IMP: 通过突变表型推断	15890200	MGI
acts upstream of or within positive regulation of DNA-templated transcription	IDA IDA: 通过直接分析推断	12782625	MGI
involved in positive regulation of binding	IDA IDA: 通过直接分析推断	26658965	MGI
involved in positive regulation of binding	IMP IMP: 通过突变表型推断	26658965	MGI
involved in positive regulation of muscle cell differentiation	IDA IDA: 通过直接分析推断	16901893	MGI
acts upstream of or within positive regulation of skeletal muscle tissue regeneration	IMP IMP: 通过突变表型推断	17028574	MGI
involved in positive regulation of snRNA transcription by RNA polymerase II	IMP IMP: 通过突变表型推断	25217815	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	7659522	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	10652346	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: 通过遗传相互作用推断	15572127	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IMP IMP: 通过突变表型推断	22638570	MGI
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: 通过突变表型推断	26658965	MGI
acts upstream of or within regulation of alternative mRNA splicing, via spliceosome	IDA IDA: 通过直接分析推断	9525963	MGI
acts upstream of or within regulation of alternative mRNA splicing, via spliceosome	IMP IMP: 通过突变表型推断	9525963	MGI
involved in regulation of gene expression	IDA IDA: 通过直接分析推断	22740650	MGI
acts upstream of or within regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	19796622	MGI
involved in skeletal muscle cell differentiation	IDA IDA: 通过直接分析推断	26658965	MGI
acts upstream of or within skeletal muscle cell differentiation	IMP IMP: 通过突变表型推断	22147266	MGI
involved in skeletal muscle cell differentiation	IMP IMP: 通过突变表型推断	26658965	MGI
acts upstream of or within skeletal muscle fiber adaptation	IMP IMP: 通过突变表型推断	19319192	MGI
acts upstream of or within skeletal muscle fiber development	IMP IMP: 通过突变表型推断	19319192	MGI
acts upstream of or within skeletal muscle tissue development	IDA IDA: 通过直接分析推断	12037571	MGI
acts upstream of or within skeletal muscle tissue development	IGI IGI: 通过遗传相互作用推断	8269513	MGI
acts upstream of or within skeletal muscle tissue development	IMP IMP: 通过突变表型推断	19531352	MGI
involved in skeletal muscle tissue regeneration	IDA IDA: 通过直接分析推断	26658965	MGI
acts upstream of skeletal muscle tissue regeneration	IMP IMP: 通过突变表型推断	17028574	MGI
involved in skeletal muscle tissue regeneration	IMP IMP: 通过突变表型推断	26658965	MGI
acts upstream of or within striated muscle cell differentiation	IMP IMP: 通过突变表型推断	17028574	MGI
acts upstream of transcription by RNA polymerase II	IGI IGI: 通过遗传相互作用推断	24301466	MGI

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in chromatin	IDA IDA: 通过直接分析推断	20833138	MGI
located in cytoplasm	IDA IDA: 通过直接分析推断	19319192	MGI
located in euchromatin	IDA IDA: 通过直接分析推断	10652346	MGI
located in myofibril	IDA IDA: 通过直接分析推断	19319192	MGI
is active in nucleus	IDA IDA: 通过直接分析推断	26658965	MGI
located in nucleus	IDA IDA: 通过直接分析推断	11711431	MGI
part of transcription regulator complex	IDA IDA: 通过直接分析推断	2503252	MGI

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

myoblast determination protein 1

Myod1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	Myod1	P10085	Suv39h1	Mus musculus	O54864	Transcription Compl	16858404
种属间	Myod1	P10085	DDX5	Homo sapiens	P17844	Pull Down	17011493
种属间	Myod1	P10085	DDX5	Homo sapiens	P17844	Anti Tag CoIP	17011493
种属间	Myod1	P10085	KAT5	Homo sapiens	Q92993	Anti Tag CoIP	21936881
种属间	Myod1	P10085	KAT5	Homo sapiens	Q92993	Pull Down	21936881
种属内	Myod1	P10085	Smarcd3	Mus musculus	Q6P9Z1	Y2H	22068056
种属内	Myod1	P10085	Smarcd3	Mus musculus	Q6P9Z1	Anti Bait CoIP	22068056
种属内	Myod1	P10085	Smarcd3	Mus musculus	Q6P9Z1	Pull Down	22068056

种属间: 跨种属相互作用 种属内: 同种属相互作用

Myod1 抗体

目录号	产品名	应用	反应物种
HY-P81175	MyoD1/Myf3 Antibody	WB, ELISA	Human, Mouse, Rat, Chicken

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS08957	MYOD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Myod1	NCBI	NCBI:4654

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Myod1 - myogenic differentiation 1 Gene

关于 Myod1

功能概要

Myod1 基因产物(1)

Myod1 蛋白互作信息

Myod1 抗体

直系同源

热门区域

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Myod1 - myogenic differentiation 1 Gene

关于 Myod1

功能概要

Myod1 基因产物(1)

Myod1 蛋白互作信息

Myod1 抗体

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z