2. Gene
  3. Cdk16 - cyclin-dependent kinase 16 Gene

Cdk16 - cyclin-dependent kinase 16 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：细胞周期蛋白依赖性激酶 16

种属: Mus musculus

同用名: Crk5; Pctk1; Pctaire1

基因 ID: 18555 | 基因类型: protein coding

关于 Cdk16

Chromosome X: 20,554,193-20,566,119 forward strand.GRCm39:CM001013.3

This gene has 8 transcripts (splice variants), 174 orthologues, 25 paralogues and is associated with 8 phenotypes. Ubiquitous expression in cerebellum adult (RPKM 14.3), adrenal adult (RPKM 9.2) and 28 other tissues.

功能概要

该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。参与多个过程，包括参与细胞对葡萄糖刺激反应的胰岛素分泌调节；细胞分泌；和精子发生。与突触小泡共定位。以多种结构表达，包括消化系统；泌尿生殖系统；免疫系统;肝;和神经系统。与人 CDK16（细胞周期蛋白依赖性激酶 16）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein serine/threonine kinase activity. Involved in several processes, including regulation of Insulin secretion involved in cellular response to glucose stimulus; secretion by cell; and spermatogenesis. Colocalizes with synaptic vesicle. Is expressed in several structures, including alimentary system; genitourinary system; immune system; liver; and nervous system. Orthologous to human CDK16 (cyclin dependent kinase 16). [provided by Alliance of Genome Resources, Apr 2022]

Cdk16 基因产物(8)

mRNA Protein Name
NM_011049.6 NP_035179.1 cyclin-dependent kinase 16 isoform 1
NM_001411705.1 NP_001398634.1 cyclin-dependent kinase 16 isoform 1
NM_001411707.1 NP_001398636.1 cyclin-dependent kinase 16 isoform 2
NM_001310456.2 NP_001297385.1 cyclin-dependent kinase 16 isoform 2
NM_001310456.2 NP_001297385.1 cyclin-dependent kinase 16 isoform 2
NM_001411705.1 NP_001398634.1 cyclin-dependent kinase 16 isoform 1
NM_001411707.1 NP_001398636.1 cyclin-dependent kinase 16 isoform 2
NM_011049.6 NP_035179.1 cyclin-dependent kinase 16 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22184064 MGI
enables protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
16461345 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in exocytosis IMP
IMP: 通过突变表型推断
16461345 MGI
involved in growth hormone secretion IMP
IMP: 通过突变表型推断
16461345 MGI
acts upstream of or within neuron projection development IMP
IMP: 通过突变表型推断
20534669 MGI
involved in neuron projection development IMP
IMP: 通过突变表型推断
21335063 MGI
involved in regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
22798068 MGI
involved in spermatogenesis IMP
IMP: 通过突变表型推断
22184064 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
26305884 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
26305884 MGI
colocalizes with synaptic vesicle IDA
IDA: 通过直接分析推断
16461345 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Cdk16 蛋白结构

STKc_PCTAIRE1

STKc_PCTAIRE1: cd07873 (161 - 457)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 496 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 16

PCTAIRE-motif protein kinase 1

cell division protein kinase 16

serine/threonine-protein kinase PCTAIRE-1

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-X0150 JSH-150 Inhibitor 98.66% 否
HY-148062 RSS0680 98.03% 否
HY-148063 DB0614 98.80% 否
HY-X0009A JSH-009 dimaleate Inhibitor / 否
HY-160213 JA397 Inhibitor / 否
HY-146680 FLT3/ITD-IN-4 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdk16 NCBI NCBI:5127
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