1. Gene
  2. Prdx2 - peroxiredoxin 2 Gene

Prdx2 - peroxiredoxin 2 Gene

种属: Mus musculus

同用名: TR; PRP; TPx; TSA; TDX1; NkefB; PrxII; TPx-B; Tdpx1; Torin; Band-8

基因 ID: 21672 | 基因类型: protein coding

关于 Prdx2

功能概要

Predicted to enable thioredoxin peroxidase activity. Involved in positive regulation of blood coagulation and removal of superoxide radicals. Acts upstream of or within several processes, including negative regulation of NF-kappaB transcription factor activity; regulation of signal transduction; and respiratory burst involved in inflammatory response. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; limb; reproductive system; and sensory organ. Orthologous to human PRDX2 (peroxiredoxin 2). [provided by Alliance of Genome Resources, Apr 2022]

Prdx2 基因产物(2)

mRNA Protein Name
NM_001317385.1 NP_001304314.1 peroxiredoxin-2
NM_011563.6 NP_035693.3 peroxiredoxin-2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17141802 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell homeostasis IMP
IMP: 通过突变表型推断
15259009 MGI
acts upstream of or within T cell proliferation IMP
IMP: 通过突变表型推断
15259009 MGI
acts upstream of extrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
15259009 MGI
acts upstream of or within hydrogen peroxide catabolic process IMP
IMP: 通过突变表型推断
15902258 MGI
acts upstream of or within hydrogen peroxide metabolic process IMP
IMP: 通过突变表型推断
15259009 MGI
acts upstream of or within negative regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
17325201 MGI
acts upstream of or within negative regulation of T cell differentiation IMP
IMP: 通过突变表型推断
16290204 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
15259009 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: 通过直接分析推断
9115640 MGI
acts upstream of or within negative regulation of lipopolysaccharide-mediated signaling pathway IMP
IMP: 通过突变表型推断
17325201 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
17325201 MGI
involved in positive regulation of blood coagulation IMP
IMP: 通过突变表型推断
20978343 MGI
acts upstream of or within regulation of hydrogen peroxide metabolic process IMP
IMP: 通过突变表型推断
17325201 MGI
involved in removal of superoxide radicals IMP
IMP: 通过突变表型推断
20978343 MGI
acts upstream of or within respiratory burst involved in inflammatory response IMP
IMP: 通过突变表型推断
17325201 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
17325201 MGI
acts upstream of or within thymus development IMP
IMP: 通过突变表型推断
15259009 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

peroxiredoxin-2

Calpromotin

Prx II-1

Trx dependent peroxide reductase 1

protector protein

thiol-specific antioxidant protein

thioredoxin peroxidase 1

thioredoxin reductase

thioredoxin-dependent peroxide reductase 1

thioredoxin-dependent peroxiredoxin 2

重组 Prdx2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73712 Peroxiredoxin-2/PRDX2 Protein, Mouse (sf9, His) Q61171/NP_035693.3 (M1-N198) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prdx2 NCBI NCBI:7001