2. Gene
  3. Fas - Fas cell surface death receptor Gene

Fas - Fas cell surface death receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Tnfrsf6

基因 ID: 246097 | 基因类型: protein coding

关于 Fas

功能概要

Enables Protease binding activity and tumor necrosis factor-activated receptor activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to estrogen stimulus; and nervous system development. Located in several cellular components, including apical dendrite; apical plasma membrane; and sarcolemma. Part of CD95 death-inducing signaling complex. Used to study IgA glomerulonephritis; brain glioma; pre-malignant neoplasm; retinal detachment; and transient cerebral ischemia. Biomarker of several diseases, including abdominal obesity-metabolic syndrome 1; artery disease (multiple); brain ischemia (multiple); eye disease (multiple); and liver disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); cystic fibrosis; hematologic Cancer (multiple); pre-eclampsia (multiple); and urinary system Cancer (multiple). Orthologous to human FAS (Fas cell surface death receptor). [provided by Alliance of Genome Resources, Apr 2022]

Fas 基因产物(1)

mRNA Protein Name
NM_139194.3 NP_631933.2 tumor necrosis factor receptor superfamily member 6 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protease binding IPI
IPI: 通过物理相互作用推断
17518537 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10386469 RGD
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
18278556 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
17518537 RGD
enables tumor necrosis factor receptor activity IMP
IMP: 通过突变表型推断
16154149 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in apoptotic signaling pathway IMP
IMP: 通过突变表型推断
16953119 RGD
involved in cellular response to cobalt ion IEP
IEP: 通过表达模式推断
15519734 RGD
involved in cellular response to cytokine stimulus IEP
IEP: 通过表达模式推断
16609999 RGD
involved in cellular response to estrogen stimulus IEP
IEP: 通过表达模式推断
15038834 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
12111799 RGD
involved in cellular response to hydrostatic pressure IEP
IEP: 通过表达模式推断
16226958 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
12031707 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
10678925 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
16987298 RGD
involved in cellular response to phenylalanine IEP
IEP: 通过表达模式推断
23940767 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
10678925 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
10029626 RGD
involved in chordate embryonic development IEP
IEP: 通过表达模式推断
11331665 RGD
involved in dendrite regeneration IMP
IMP: 通过突变表型推断
18692025 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
10632538 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
10084951 RGD
involved in negative regulation of Schwann cell migration IMP
IMP: 通过突变表型推断
29970988 RGD
involved in negative regulation of Schwann cell proliferation IMP
IMP: 通过突变表型推断
29970988 RGD
involved in ovarian follicle atresia IEP
IEP: 通过表达模式推断
8612534 RGD
involved in ovulation cycle IEP
IEP: 通过表达模式推断
16461545 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
15519734 RGD
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
15519734 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
23940767 RGD
involved in regulation of apoptotic process IMP
IMP: 通过突变表型推断
16582846 RGD
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17991709 RGD
involved in regulation of lipid storage IEP
IEP: 通过表达模式推断
27939985 RGD
involved in response to cycloheximide IEP
IEP: 通过表达模式推断
9253159 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
17105443 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
16099864 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
27939985 RGD
involved in response to fluoride IEP
IEP: 通过表达模式推断
20568470 RGD
involved in response to growth factor IEP
IEP: 通过表达模式推断
18692025 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
16870148 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
30301943 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17899301 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19616844 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
27939985 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
16392621 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
17900647 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16687611 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
17195944 RGD
involved in telencephalon development IEP
IEP: 通过表达模式推断
10024361 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CD95 death-inducing signaling complex IDA
IDA: 通过直接分析推断
16493077 RGD
located in apical dendrite IDA
IDA: 通过直接分析推断
10024361 RGD
located in apical plasma membrane IDA
IDA: 通过直接分析推断
12861046 RGD
located in cell surface IDA
IDA: 通过直接分析推断
18045865 RGD
part of death-inducing signaling complex IDA
IDA: 通过直接分析推断
17518537 RGD
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
17195944 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
12522536 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15038834 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
17518537 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
10715265 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
11332701 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor receptor superfamily member 6

CD95 antigen

FASLG receptor

Fas (TNF receptor superfamily, member 6)

Fas antigen (ATP1)

Fas receptor

Tumor necrosis factor receptor superfamily, member 6

apo-1 antigen

apoptosis-mediating surface antigen FAS

重组 Fas 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73048 Fas/CD95 Protein, Rat (HEK293, Fc) Q63199 (Q22-K170) ≥95%
HY-P73049 Fas/CD95 Protein, Rat (HEK293, His) Q63199 (Q22-K170) ≥95%

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-16046 Rimiducid 99.81% Phase 3
HY-13721 Phenoxodiol 99.76% Phase 3
Pre-clinical Phase
生物活性分子 (32)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12325 GSK2194069 Inhibitor 99.84% 否
HY-14414 GSK4112 Inhibitor 99.87% 否
HY-133897 (Rac)-Indoximod 98.13% 否
HY-150190 F5446 99.38% 否
HY-100755 KR-33493 Inhibitor 99.75% 否
HY-103243 TCPOBOP Inhibitor 98.67% 否
HY-16100 BI 99179 Inhibitor 99.38% 否
HY-101849 Fasentin ≥98.0% 否
HY-N0704 Agrimol B 99.75% 否
HY-N0686 Pseudoprotodioscin Inhibitor 98.76% 否
HY-P10102 Kp7-6 Inhibitor 99.77% 否
HY-Y0598 trans-Chalcone 98.65% 否
HY-103348 Boc-Asp(OMe)-fluoromethyl ketone Inhibitor ≥98.0% 否
HY-112716 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride Inhibitor ≥99.0% 否
HY-129624A Bisindolylmaleimide VIII acetate 99.68% 否
HY-N6777 Penicillic acid Inhibitor 99.83% 否
HY-108610A Edelfosine Inducer ≥98.0% 否
HY-103347 M50054 Inhibitor 98.44% 否
HY-N7930 Crenulatin ≥99.0% 否
HY-E70404 FastTaq DNA Polymerase(5'→3' exo-) / 否
HY-103323 Fas C-Terminal Tripeptide Inhibitor / 否
HY-113963 Ac-​IETD-​CHO Inhibitor / 否
HY-146197 Apoptotic agent-1 Inducer / 否
HY-167879 (Rac)-NPD6433 Inhibitor / 否
HY-P3779 Amyloid 17-42 Inducer / 否
HY-P5798 Fasciculin-I Inhibitor / 否
HY-RS04751 FAS Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-118147 ML356 Inhibitor / 否
HY-129624 Bisindolylmaleimide VIII / 否
HY-167879A NPD6433 Inhibitor / 否
HY-P10401 TAT-GluR6-9c Antagonist / 否
HY-P5797 Fasciculin-II Inhibitor / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99133 Anti-Mouse Fas Ligand Antibody (MFL3) Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fas NCBI NCBI:355
Macaca fascicularis Fas NCBI NCBI:102140989
Mus musculus Fas NCBI NCBI:14102
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z