Stat5b - signal transducer and activator of transcription 5B Gene

中文名称：信号转导和转录激活因子 5 B

种属: Rattus norvegicus

关于 Stat5b

功能概要

该基因编码的蛋白可启动 DNA 结合活性； DNA结合转录因子活性；和染色质结合活性。参与多个过程，包括细胞对表皮生长因子刺激的反应；黄体化；和受体信号通路通过 JAK-STAT。位于细胞质和细胞核中。该基因的人类直向同源基因与免疫失调的生长激素不敏感综合征 1 和免疫失调的生长激素不敏感综合征 2 相关。与人类 STAT5B（信号转导和转录激活因子 5B）直系同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA binding activity; DNA-binding transcription factor activity; and chromatin binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; luteinization; and receptor signaling pathway via JAK-STAT. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5B (signal transducer and activator of transcription 5B). [provided by Alliance of Genome Resources, Apr 2022]