2. Gene
  3. Tnik - TRAF2 and NCK interacting kinase Gene

Tnik - TRAF2 and NCK interacting kinase Gene

  • 基因
  • 相关产品
  • 直系同源

中文名称：TRAF2 和 NCK 相互作用激酶

种属: Rattus norvegicus

同用名: RGD1561817

基因 ID: 294917 | 基因类型: protein coding

关于 Tnik

Primary_assembly 2: 111,184,387-111,580,750 forward strand.mRatBN7.2:CM026975.1

This gene has 6 transcripts (splice variants), 268 orthologues, 36 paralogues and is associated with 8 phenotypes.

功能概要

预测该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。参与树突形态发生的正调控。在谷氨酸能突触中活跃；突触后密度，细胞内成分；和突触前。该基因的人类直系同源物与常染色体隐性非综合征性智力障碍有关。与人类 TNIK（TRAF2 和 NCK 相互作用激酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of dendrite morphogenesis. Is active in glutamatergic synapse; postsynaptic density, intracellular component; and presynapse. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TNIK (TRAF2 and NCK interacting kinase). [provided by Alliance of Genome Resources, Apr 2022]

Tnik 基因产物(1)

mRNA Protein Name
NM_001106422.1 NP_001099892.1 TRAF2 and NCK-interacting protein kinase

相关产品

Pre-clinical Phase
生物活性分子 (21)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100830 NCB-0846 Inhibitor 99.61% 否
HY-111754 DMX-5804 Inhibitor 99.83% 否
HY-10371 Pim1/AKK1-IN-1 Inhibitor 98.20% 否
HY-124745 KY-05009 99.24% 否
HY-145293 TNIK-IN-3 Inhibitor 99.88% 否
HY-124762 TNIK-IN-1 98.86% 否
HY-143437 TNIK-IN-5 Inhibitor 99.75% 否
HY-156816 ON 108600 Inhibitor 99.73% 否
HY-N3127 Orobol Inhibitor 99.28% 否
HY-156502 TINK-IN-1 Inhibitor 98.02% 否
HY-156817 TNIK-IN-6 96.92% 否
HY-156818 TNIK-IN-7 99.90% 否
HY-143436 TNIK-IN-4 Inhibitor / 否
HY-145292 TNIK-IN-2 / 否
HY-156523 TNIK&MAP4K4-IN-1 / 否
HY-162314 TNIK-IN-8 Inhibitor / 否
HY-163478 TNIK-IN-9 Inhibitor / 否
HY-RS14831 TNIK Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14832 Tnik Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14833 Tnik Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-160623 TNIK&MAP4K4-IN-2 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnik NCBI NCBI:23043
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