2. Gene
  3. Bag3 - BCL2-associated athanogene 3 Gene

Bag3 - BCL2-associated athanogene 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bis; mg638

基因 ID: 29810 | 基因类型: protein coding

关于 Bag3

功能概要

Predicted to enable adenyl-nucleotide exchange factor activity and chaperone binding activity. Involved in muscle cell cellular homeostasis. Acts upstream of or within several processes, including cellular response to mechanical stimulus; extrinsic apoptotic signaling pathway in absence of ligand; and protein stabilization. Located in Z disc. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and respiratory system. Used to study dilated cardiomyopathy 1HH. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1HH and myofibrillar myopathy 6. Orthologous to human BAG3 (BAG cochaperone 3). [provided by Alliance of Genome Resources, Apr 2022]

Bag3 基因产物(1)

mRNA Protein Name
NM_013863.5 NP_038891.4 BAG family molecular chaperone regulator 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11527400 MGI
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
20884878 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to mechanical stimulus IMP
IMP: 通过突变表型推断
16936253 MGI
acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: 通过直接分析推断
11527400 MGI
involved in muscle cell cellular homeostasis IMP
IMP: 通过突变表型推断
16936253 MGI
acts upstream of or within negative regulation of striated muscle cell apoptotic process IMP
IMP: 通过突变表型推断
16936253 MGI
acts upstream of or within protein stabilization IMP
IMP: 通过突变表型推断
20884878 MGI
acts upstream of striated muscle cell apoptotic process IMP
IMP: 通过突变表型推断
16936253 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
16936253 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

BAG family molecular chaperone regulator 3

BAG-3

Bcl-2-binding protein Bis

Bcl-2-interacting death suppressor

bcl-2-associated athanogene 3

Bag3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Bag3 Q9JLV1 EBNA-LP Epstein-Barr virus Q8AZK7
Anti Bait CoIP
18457437
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Bag3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71848 BAG-3 Protein, Mouse (P.pastoris, His) Q9JLV1 (2S-577P) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-117282 JG-98 99.88% 否
HY-156278 FB49 Inhibitor 99.76% 否
HY-RS01344 BAG3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bag3 NCBI NCBI:9531
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