2. Gene
  3. Hip1r - huntingtin interacting protein 1 related Gene

Hip1r - huntingtin interacting protein 1 related Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mKIAA0655

基因 ID: 29816 | 基因类型: protein coding

关于 Hip1r

功能概要

Enables several functions, including SH3 domain binding activity; clathrin binding activity; and protein dimerization activity. Involved in several processes, including negative regulation of supramolecular fiber organization; positive regulation of clathrin coat assembly; and regulation of gastric acid secretion. Acts upstream of or within receptor-mediated endocytosis. Located in several cellular components, including apical plasma membrane; clathrin-coated pit; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; bone; central nervous system; genitourinary system; and sensory organ. Orthologous to human HIP1R (Huntingtin interacting protein 1 related). [provided by Alliance of Genome Resources, Apr 2022]

Hip1r 基因产物(1)

mRNA Protein Name
NM_145070.3 NP_659507.3 huntingtin-interacting protein 1-related protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH3 domain binding IDA
IDA: 通过直接分析推断
17318189 MGI
enables actin binding IDA
IDA: 通过直接分析推断
10613908 MGI
enables actin filament binding IDA
IDA: 通过直接分析推断
11564758 MGI
enables clathrin adaptor activity IDA
IDA: 通过直接分析推断
11564758 MGI
enables clathrin binding IDA
IDA: 通过直接分析推断
11564758 MGI
enables clathrin light chain binding IPI
IPI: 通过物理相互作用推断
15533940 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15090612 MGI
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
15533940 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
11564758 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in clathrin coat assembly IDA
IDA: 通过直接分析推断
11564758 MGI
involved in digestive system development IMP
IMP: 通过突变表型推断
18535670 MGI
involved in membrane organization IMP
IMP: 通过突变表型推断
18535670 MGI
involved in negative regulation of Arp2/3 complex-mediated actin nucleation IDA
IDA: 通过直接分析推断
17318189 MGI
involved in negative regulation of actin filament polymerization IDA
IDA: 通过直接分析推断
17318189 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
18535670 MGI
involved in positive regulation of clathrin coat assembly IDA
IDA: 通过直接分析推断
15533940 MGI
acts upstream of or within receptor-mediated endocytosis IDA
IDA: 通过直接分析推断
10613908 MGI
involved in regulation of actin cytoskeleton organization IGI
IGI: 通过遗传相互作用推断
14742709 MGI
involved in regulation of gastric acid secretion IMP
IMP: 通过突变表型推断
18535670 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
18535670 MGI
located in cell cortex IDA
IDA: 通过直接分析推断
11564758 MGI
located in clathrin-coated pit IDA
IDA: 通过直接分析推断
10613908 MGI
located in clathrin-coated vesicle IDA
IDA: 通过直接分析推断
10613908 MGI
located in cytoskeleton IDA
IDA: 通过直接分析推断
10613908 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
10613908 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

huntingtin-interacting protein 1-related protein

HIP1-related protein

Hip1r 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Hip1r Q9JKY5 SH3KBP1 Homo sapiens Q96B97
Anti Tag CoIP
15090612
种属内
Hip1r Q9JKY5 Cttn Mus musculus Q60598
Pull Down
17318189
种属间
Hip1r Q9JKY5 Egfr Rattus norvegicus G3V6K6
Anti Tag CoIP
30574069
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06180 HIP1R Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hip1r NCBI NCBI:9026
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